Domtar Inc.

Magdy M Abdel-Malik

Manssur Yalpani

A product comprising a water soluble, high molecular weight aminoalkyl-derivative of hydroxyalkyl-cellulose. The molecular weight of said cellulose is at least 50,000 daltons. One of the methods to obtain the product comprises reacting a hydroxyalkyl cellulose in a basic aqueous medium, in the presence of halogenalkylaminohalide compounds, to obtain a hydroxyalkyl cellulose having an alkylamino group which can be used as such or further reacted in the presence of an amide reducing agent, for instance sodium cyanoborohydride and a carbohydrate residue selected from the group consisting of mono-, di-, oligo-saccharides and starch.

Aminoalkyl-derivatives of hydroxyalkyl-celluloses

New amines and amides of carboxylated polysaccharides having the nitrogen of the amido and amino groups directly attached to the polysaccharides and method of making same, based on reacting in solution a material having carboxyl-containing polysaccharides, such as carboxymethyl cellulose, with ammonium donors having the general formula &gt;NH such as primary and secondary amine reagents and with or without a reducing agent to obtain amides or amines. These products may be used for instance in biological separations, for the immobilization of proteins, for the removal of metal ions, as thickeners, and as suspension agents.

Processes for the preparation of amides and amines from a material

New Amines and amides of carboxylated polysaccharides having the nitrogen of the amido and amino groups directly attached to the polysaccharides and method of making same, based on reacting in solution a material having carboxyl-containing polysaccharides, such as carboxymethyl cellulose, with ammonium donors having the general formula &gt;NH such as primary and secondary amine reagents and with or without a reducing agent to obtain amides or amines. These products may be used for instance in biological separations, for the immobilization of proteins, for the removal of metal ions, a thickeners, and as suspension agents.

A method to selectively oxidize a polyglucose, on the oxygen of the hydroxy groups of the C-6 position of the glucose rings, while substantially maintaining the degree of polymerization of the polyglycosidic units, comprising heating a 6-sulfonyl polyglucose, for instance 6-O-para-(P)-toluene sulfonyl polyglucose with dimethyl sulfoxide (DMSO) in the presence of at least a catalytic amount of a catalyst selected from a member of the group consisting of: symmetrical--collidine, sodium bicarbonate and pyridine, to produce a polyglucose having aldehyde groups on the oxygen of the hydroxyl on the C-6 position of the glucose rings. In a preferred embodiment when pyridine is selected, this method enables use of that reaction to obtain other new products having other functional groups, mainly on the C-6 position of the glucose rings, without having to purify the aldehyde which may serve as intermediate.

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Kirkland, Canada

Magdy M Abdel-Malik