Intel Corporation

Madoo Varma

Xing Su

Handong Li

Kai Wu

Oguz Hasan Elibol

Grace M Credo

Noureddine Tayebi

Jonathan S Daniels

Drew Hall

Various embodiments provide devices, methods, and systems for high throughput biomolecule detection using transducer arrays. In one embodiment, a transducer array made up of transducer elements may be used to detect byproducts from chemical reactions that involve redox genic tags. Each transducer element may include at least a reaction chamber and a fingerprinting region, configured to flow a fluid from the reaction chamber through the fingerprinting region. The reaction chamber can include a molecule attachment region and the fingerprinting region can include at least one set of electrodes separated by a nanogap for conducting redox cycling reactions. In embodiments, by flowing the chamber content obtained from a reaction of a latent redox tagged probe molecule, a catalyst, and a target molecule in the reaction chamber through the fingerprinting region, the redox cycling reactions can be detected to identify redox-tagged biomolecules.

High throughput biochemical detection using single molecule fingerprinting arrays

Growing community of inventors

Palo Alto, CA, United States of America

Madoo Varma