Corixa Corporation

Madeleine Joy Meagher

Jiangchun Xu

John A Stolk

Davin C Dillon

Jennifer L Mitcham

Darrick Carter

Yasir A W Skeiky

Thomas S Vedvick

Patricia Dianne McNeill

Raymond L Houghton

Gary R Fanger

Marc W Retter

Susan L Harlocker

Michael D Kalos

Yuqiu Jiang

Aijun Wang

Robert A Henderson

Samuel X Li

Craig H Day

William T Hepler

Teresa M Foy

Carlota Vinals Y De Bassols

Yoshihiro Watanabe

John Hural

Michael J Lodes

Tongtong Wang

Heather Secrist

Darin R Benson

Ta Deng

Compositions and methods for the therapy and diagnosis of cancer, particularly prostate cancer, are disclosed. Illustrative compositions comprise one or more prostate-specific polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly prostate cancer.

Prostate-specific polynucleotide compositions

Compositions and methods for the therapy and diagnosis of prostate cancer

Compositions and methods for the therapy and diagnosis of cancer, such as colon cancer, are disclosed. Compositions may comprise one or more colon tumor proteins, immunogenic portions thereof, or polynucleotides that encode such portions. Alternatively, a therapeutic composition may comprise an antigen presenting cell that expresses a colon tumor protein, or a T cell that is specific for cells expressing such a protein. Such compositions may be used, for example, for the prevention and treatment of diseases such as colon cancer. Diagnostic methods based on detecting a colon tumor protein, or mRNA encoding such a protein, in a sample are also provided.

Compounds for immunotherapy and diagnosis of colon cancer and methods for their use

Growing community of inventors

Seattle, WA, United States of America

Madeleine Joy Meagher