Council of Scientific and Industrial Research

Madalsa Bargotra

Ghulam Nabi Qazi

Naresh Kumar Satti

Krishan Avtar Suri

Om Parkash Suri

Bal Krishan Chandan

Bupinder Singh Jaggi

Bishan Datt Gupta

Vikram Bhardwaj

Vishwa Nath Gupta

Neelam Sharma

Jyotsna Suri

The present invention relates to a synergistic formulation comprising trans-tetracos-15-enoic acid (t-TCA) and andrographolide (AP) in the ratio ranging between 1:7 to 7:1 (w/w), useful in hepatoprotection; and a process for the preparation of a synergistic formulation comprising trans-tetracos-15-enoic acid (t-TCA) and andrographolide (AP) useful in hepatoprotection, said process comprising steps of grounding the particles of the t-TCA and AP into fine particles, mixing the fine particles in ratio ranging between 1:7 to 7:1 (w/w), and grinding the mixture to obtain formulation, and also, a method of hepatoprotection of a subject using the synergistic formulation comprising trans-tetracos-15-enoic acid (t-TCA) and andrographolide (AP), said method comprising the steps of administering the formulation to the subject.

Synergistic hepatoprotective composition and a method thereof

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Jammu, India

Madalsa Bargotra