University of Delaware

Maciek Antoniewicz

Eleftherios Terry Papoutsakis

Alan Fast

Robert Kyle Bennett

William Brian Whitaker

Nicholas Richard Sandoval

Sergios Nicolaou

Vasiliki Falara

Jacqueline Gonzalez

A non-naturally occurring microbe capable of growing in a medium comprising methanol is provided. The methanol contributes to a significant percentage (e.g., at least 40%) of the carbon source for the non-naturally occurring microbe, which expresses heterologous methanol dehydrogenase (MDH) and heterologous ribulose monophosphate (RuMP) pathway enzymes. Methods for producing liquid fuels and chemicals by the non-naturally occurring microbe and methods for preparing the non-naturally occurring microbe are also provided.

Synthetic methylotrophy to liquid fuels and chemicals

Growing community of inventors

Baltimore, MD, United States of America

Maciek Antoniewicz