Xdx, Inc.

Archimedes, Inc.

Evidera Archimedes, Inc.

MacDonald Morris

Kirk E Fry

Steven Rosenberg

Robert Woodward

Jay Wohlgemuth

Ngoc Ly

James Prentice

David M Eddy

Joshua Adler

A method and apparatus for predicting a health benefit for an individual is provided. Outcomes from a first simulation on a set of simulated individuals reflecting a population are stored and used to determine a first risk function and corresponding cost values. Outcomes from a second simulation on a set of simulated individuals reflecting having a healthcare intervention are stored and used to determine a second risk function reflecting the intervention and corresponding cost values of the intervention. A benefit function is derived from the difference of the first and second risk functions. A cost function that describes the cost of the intervention is derived from the respective cost values. The derived benefit function and cost function are used to predict the corresponding benefit and cost of the healthcare intervention for a given individual. Individuals can be ranked by degree of expected benefit.

Estimating healthcare outcomes for individuals

A method of determining a quality of care provided by a healthcare provider to individuals in a population is provided. A data processing apparatus that has one or more processors is disclosed. Data representing biomarkers for individuals in a population is received. Baseline and present risks are determined. Risk reduction values are determined. Based on the current risk reduction, a quality score is determined. A scale is created, and the quality score is mapped to the scale. The global quality score of the disclosure provides numerous benefits over past performance measures.

Healthcare quality measurement

Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described.

Methods and compositions for diagnosing and monitoring transplant rejection

Growing community of inventors

Atherton, CA, United States of America

MacDonald Morris