Novo Nordisk A/s

Other

Unilever Plc

Novozymes A/s

Lever Brothers Company, Division of Conopco, Inc.

Maarten Robert Egmond

Sven Branner

Ole Hvilsted Olsen

Sven Hastrup

Johan Haverkamp

Eric Casteleijn

Dorrit A Aaslyng

Merete Simonsen

Nina Eriksen

John David Marugg

Arnoldus Theodorus Anthonius Mooren

Wouter Musters

Poul Lindegaard

Jakob De Vlieg

Leif N&oslash;rskov-Lauritsen

Allan Svendsen

Cornelis T Verrips

Claus Von Der Osten

John D Marugg

Amir Maximiliaan Batenburg

Leif No slashedrskov-Lauritsen

Leon Gerardus Frenken

Eric Castelijn

Arnoldus Theodorus Mooren

Lisbeth Hedegangrd

Leif Norskov-Lauritsen

The present invention relates to enzymes produced by mutating the genes for a number of subtilisin proteases and expressing the mutated genes in suitable hosts are presented. The enzymes exhibit improved wash performance in comparison to their wild type parent enzymes. The enzymes are well-suited for use in detergent compositions.

Modified subtilisins and detergent, compositions containing same

Modified subtilisins and detergent compositions containing same

Stabilized enzymes and detergent compositions

The present invention relates to modified subtilisins comprising a mutation in an amino acid sequence of a subtilisin at a position selected from the group consisting of 1, 2, 3, 4, 6, 9, 10, 12, 14, 15, 17, 18, 19, 20, 21, 22, 24, 25, 27, 36, 37, 38, 40, 41, 43, 44, 45, 46, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 75, 76, 77, 78, 79, 87, 89, 91, 94, 97, 98, 99, 100, 101, 103, 104, 105, 106, 107, 108, 109, 112, 113, 115, 116, 117, 118, 120, 126, 128, 129, 130, 131, 133, 134, 136, 137, 140, 141, 143, 144, 145, 146, 155, 156, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 170, 171, 172, 173, 181, 182, 183, 184, 185, 186, 188, 189, 191, 192, 194, 195, 197, 204, 206, 209, 210, 211, 212, 213, 214, 215, 216, 217, 218, 235, 236, 237, 238, 239, 240, 241, 242, 243, 244, 245, 247, 248, 249, 251, 252, 253, 254, 255, 256, 257, 259, 260, 261, 262, 263, 265, 269, 271, 272 and 275. The present invention also relates to detergent compositions comprising a modified subtilisin of the present invention.

Lipase enzymes including mutant lipase enzymes, e.g. from Pseudomonas species, are produced and modified by recombinant DNA technique. The enzymes are applicable in detergent and cleaning compositions, with advantages for example of improved stability to proteolytic digestion.

Microbial lipase muteins and detergent compositions comprising same

This invention relates to enzymes, to rDNA techniques applicable for example to their production, to mutated genes, vectors and mutant and transformed microorganisms useful in their production, and to their uses including for example enzymatic detergent and cleaning compositions containing them.

Detergent compositions comprising a modified subtilisin

Subtilisin mutants

Growing community of inventors

Linschoten, Netherlands

Maarten Robert Egmond