King Abdulaziz University

Maan Talaat Khayat

Abdelsattar Mansour Omar

Moustafa Elsayed El-Araby

Martin K Safo

Azizah M Malebari

Farid Ahmed

Dhaval Shah

Mahmoud A Elfaky

Hani Zakariah Asfour

Faida Hassan Bamane

Ghufran A Alhowswi

Mahmoud Abdelkhalek El-Faky

Fatma M Alhaity

Muna M Albeeshy

Sameh Hamdy Abdelmageed Soror

Khadijah A Mohammad

Yosra A Muhammad

Hani Mohammed Z Choudhry

Amer Hamzah O Asseri

Mohammad Imran Khan

Mahmood Hassan Dalhat

Mohammed Razeeth S Mohammed

Majed Abdullah A Alharbi

Therapeutic compounds containing an arylacetamide core pending N-benzyl group. Also described are pharmaceutical compositions incorporating the therapeutic compounds and a method for inhibiting AMP-activated kinase (AMPK) and their use thereof for treating breast and pancreatic cancer with the specified compounds.

Arylacetamides as AMP-activated protein kinase inhibitors and their use for treatment of breast cancer

Therapeutic compounds containing a phenyl core and amide link(s). Also described are pharmaceutical compositions incorporating the therapeutic compounds and a method for treating cancer with the compounds. These compounds are cytotoxic to stomach, colon, breast, and leukemia cancer cell lines via dual inhibition of Src kinases and tubulin.

Method for treating stomach cancer

Method for treating a patient having a colon cancer

Method for making anti-cancer compounds

Pharmaceutical composition for treating cancer

Method for treating a patient having cancer

Cytotoxic compounds, pharmaceutical compositions thereof, and methods of treating cancer

Imidazole-based compounds as hepatitis C virus (HCV) inhibitors. The compounds have an imidazole core that is disubstituted via amide links. Also described are a pharmaceutical composition incorporating the imidazole-based compound, a method of preparing these compounds, and a method for using the pharmaceutical composition in the treatment of HCV infection.

Imidazole-based compounds as hepatitis C virus inhibitors

Compounds for the chemosensitization of antibiotic resistant bacteria such as multidrug resistant (MDR)(Pa) are provided. The compounds inhibit the MDR efflux proteins and re-sensitize the bacteria towards killing by antibiotics. Thus, the compounds are used in combination with antibiotics to treat or prevent infections caused by MDR bacteria.

Chemosensitization of resistantby synthetically related compounds

Amide group-containing compounds and use for cancer treatment

Compounds for inhibiting NS3 and compositions containing the inhibited protein

Growing community of inventors

Jeddah, Saudi Arabia

Maan Talaat Khayat