Lifescan Scotland Limited

Cilag International Gmbh

Lifescan IP Holdings, LLC

Lynsey Whyte

Antony Smith

Neil Whitehead

David McColl

Scott J Sloss

David Mccoll

Oliver William Davies

Brian Guthrie

Rossano Claudio Massari

Manuel Alvarez-Icaza

Damian Edward Haydon Baskeyfield

Christian Fabio Forlani

John Dilleen

Oliver William Hardwicke Davies

Elaine Leiper

Robert Marshall

Ramsay Raymond Donald Darling

Russell Bain

Timothy Lloyd

Alexander Cooper

Joanne McIlrath

Robert Hamish MacLeod

Darren Mitchell

Thomas Joseph 0'Reilly

Robert Hamish Macleod

Scott Sloss

David Morris

Thomas Joseph 0'reilly

Damian Edward Baskeyfield

John William Dilleen

Karn Campbell

Robert MacLeod

Ramsay Darling

James Mclaren

Stuart Phillips

An analytical test strip for the determination of an analyte (such as glucose and/or hematocrit) in a bodily fluid sample (such as a whole blood sample) includes a first capillary sample-receiving chamber, a second capillary sample-receiving chamber, and a physical barrier island disposed between the first and second capillary sample-receiving chambers. Moreover, the physical island barrier is disposed such that bodily fluid sample flow between the first capillary sample-receiving chamber and the second capillary sample-receiving chamber is prevented during use of the analytical test strip.

Analytical test strip with capillary sample-receiving chambers separated by a physical barrier island

Analyte test strip design

An electrochemical-based analytical test strip for the determination of an analyte (such as glucose) in a bodily fluid sample (for example, a whole blood sample) and/or a characteristic of the bodily fluid sample (e.g., hematocrit) includes a sample-entry chamber with a sample-application opening disposed on an end edge of the electrochemical-based analytical test strip, and first and second sample-determination chambers, each in direct fluidic communication with the sample-entry chamber. The electrochemical-based analytical test strip also includes first and second electrodes (such as first and second hematocrit electrodes) disposed in the first sample-determination chamber, and a third and fourth electrodes (for example working and reference electrodes) disposed in the second sample-determination chamber. Moreover, the first and second sample-determination chambers intersect the sample-entry chamber perpendicular (or nearly perpendicular) to one another and the first sample-determination chamber also intersects the sample-entry chamber in an aligned manner.

End-fill electrochemical-based analytical test strip with perpendicular intersecting sample-receiving chambers

Various embodiments for methods and systems that allow for detecting of a direction in which a sample is flowing towards a plurality of electrodes and detecting a fill error of an electrochemical test strip.

Methods and systems to determine fill direction and fill error in analyte measurements

An electrochemical-based analytical test strip for the determination of an analyte (such as glucose) in a bodily fluid sample (for example, a whole blood sample) and/or a characteristic of the bodily fluid sample (for example, hematocrit) includes a first sample-receiving chamber with first and second sample-application openings, and first and second electrodes. The first and second electrodes are disposed in the first sample-receiving chamber between the first and second sample-application openings. The electrochemical-based analytical test strip also includes a second sample-receiving chamber and a plurality of electrodes disposed in the second sample-receiving chamber. In addition, the second sample-receiving chamber intersects the first sample-receiving chamber between the first and second electrodes, thereby defining a chamber intersection.

Electrochemical-based analytical test strip with intersecting sample-receiving chambers

An electrochemical-based analytical test strip includes an electrically-insulating substrate, a patterned conductive layer disposed over the electrically-insulating substrate, a patterned insulating layer disposed over the patterned conductive layer, an enzymatic reagent layer disposed over the patterned conductive layer, a patterned adhesive layer disposed above the enzymatic reagent layer and a top layer disposed over the enzymatic reagent layer. In addition, the test strip has a sample-receiving chamber defined by the electrically-insulating substrate, the patterned conductive layer, the patterned insulating layer, the enzymatic reagent layer, the patterned adhesive layer and the top layer. The sample receiving chamber of the test strip has a working portion and a non-working portion and the top layer has a first portion and an opaque second portion. The first portion is configured such that a user can view the working portion of the sample-receiving chamber through the first portion of the top layer, while the opaque second portion is configured to preclude a user from viewing the non-working portion of the sample-receiving chamber.

Analytical test strip with minimal fill-error sample viewing window

This invention describes a method of reducing the effect of interfering compounds in a bodily fluid when measuring an analyte using an electrochemical sensor. In particular, the present method is applicable to electrochemical sensors where the sensor includes a substrate, first and second working electrodes, and a reference electrode and either the first and second or only the second working electrode include regions which are bare of reagent. In this invention, an algorithm is described with mathematically corrects for the interference effect using the test strip embodiments of the present invention.

Method of reducing the effect of direct interference current in an electrochemical test strip

Electrochemical test strip

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Newtonmore, United Kingdom

Lynsey Whyte