Ciba-geigy Corporation

Lynn C Winterton

Kai C Su

Barbara L Heyl

Jack C White

William M Hung

Fu-Pao Tsao

A dispensing device having a container body defining a solution retaining chamber therein, the container having an outlet for dispensing the solution from the chamber and means for removing a component from the solution as the solution is dispensed from the chamber through the container outlet. A method is provided for administering to a patient a pharmacologically active substance which substance is stable only at a pH value which is extreme in the acidic or alkaline region and at which pH value the substance cannot be administered without causing discomfort and/or injury to the patient. The substance is maintained in a solution or dispersion at the pH at which it is stable until the time of administration. At this time the substance is administered through a chamber containing an ion exchange resin which changes the pH of the solution or dispersion to a value which will not cause discomfort and/or injury to the patient.

Method for removing components from solutions

Apparatus for removing components from solutions

The efficacy of buffered H.sub.2 O.sub.2 disinfecting formulations for contact lenses is improved by incorporationg into such formulations a surface active agent.

Hydrogen peroxide disinfection solutions

A method is provided for the sterilization or disinfection of an object in need of such treatment. The object is immersed in a sterilizing or disinfecting solution containing an antimicrobial effective amount of at least one cationic or at least one anionic antimicrobial agent in the presence of a scavenger element containing a scavenger material which is a cationic exchange resin or an anionic exchange resin. Over a period of time, the scavenger element removes from the solution the cationic or anionic antimicrobial agent at a rate which permits sterilization or disinfection of the object and which prevents undesirable build-up of the antimicrobial agent in or on the object. The object is allowed to remain in the solution for a time sufficient for the scavenger element to remove a sufficient amount of the antimicrobial agent to render the object safe for use for its intended purpose and the object is then removed from the solution. The method is particularly useful in the sterilization or disinfection of contact lenses. An apparatus for sterilizing or disinfecting objects in need of such treatment is also disclosed.

Method and container for sterilizing and disinfecting

A contact lens conditioning solution which has a polyoxyethylene-polyoxypropylene substituted ethylenediamine nonionic surfactant (Poloxamine type) having a hydrophile-lipophile balance of seven or below and a carrier vehicle. A polyoxyethylene-polyoxypropylene nonionic surfactant (Poloxamer type) having a hydraulic-lipophile balance of seven or below and a polyoxyethylene concentration of less than about 20% by weight of the polyoxyethylene-polyoxypropylene nonionic surfactant may also be included in the solution.

Conditioning solution for contact lenses and a method of using the same

The invention relates to the use of dodecyl-dimethyl-(2 phenoxyethyl)-ammonium bromide as an antimicrobial agent to be a preservative for ophthalmic drug solutions, in disinfecting solutions, as well as in preservatives for aqueous ocular solutions for contact lenses.

Antimicrobial ophthalmic solutions containing dodecyl-dimethyl-(2

A dispensing device having a container body defining a solution retaining chamber therein, the container having an outlet for dispensing the solution from the chamber and means for removing a component from the solution as the solution is dispensed from the chamber through the container outlet.

Process for removing components from solutions

An ophthalmic solution for improving the exchange of fluid in the area outside a hydrogel contact lens with the fluid in the area underneath the hydrogel contact lens comprising:

Ophthalmic solutions and methods for improving the comfort and safety of

An opthalmic cleaning composition for cleaning a contact lens comprising an effective amount of a water soluble particulate compound for removing proteinaceous, lipid and other non-proteinaceous deposits on the contact lens, wherein the particulate compound is suspended in a predominately non-aqueous water-miscible organic liquid medium which is substantially a non-solvent for the particulate compound, and a method of cleaning a contact lens employing such composition.

Growing community of inventors

Roswell, GA, United States of America

Lynn C Winterton