Radiometer Medical Aps

Radiometer Medical A/s

Fibervisions A/s

Lydia Dahl Clausen

Thomas Kjaer

Thomas Steen Hansen

Allan Milton Byrnard

Katharine Dyrmose-Jensen

Jesper Svenning Kristensen

Bjo Slashedrn Marcher

Arne Jensen

Pauline Newlove

Signe Lagoni

Thomas KJÆR

Thomas Kjær

Ion selective membranes and the preparation thereof, such as magnesium ion selective membranes and the preparation thereof. In particular, the invention describes improved PVC polymer blends for use in ion selective membranes. The invention furthermore relates to electrodes and potentiometric sensors comprising such membranes and the use thereof for determining ion concentrations in samples.

Magnesium ion selective PVC membranes

The present application discloses a planar enzyme sensor for measuring the concentration of an analyte in a solution comprising a substrate of an electrically insulating material supporting an electrode layer of an electrically conductive material. The substrate and electrode layer have a plurality of layers disposed thereon which include an enzyme layer and a microporous outer layer covering the enzyme layer, wherein the outer layer comprises a continuous phase of a water-resistant polymer (e.g. a polyvinylacetate or an acrylate copolymer), a protein (e.g. an enzyme) embedded in the continuous phase, and possibly polytetrafluoroethylene particles. The enzyme and the polytetrafluoroethylene particles provide a controlled porosity to the outer membrane.

Outer layer for enzyme sensors

The present disclosure relates to an improved enzyme sensor comprising a cover membrane layer of a porous polymeric material, the outer surface and pore mouths of at least one face of the porous polymeric material being covered by a hydrophilic polymer. The sensor is useful determining the presence or amount of biological analytes, e.g., glucose, lactate, creatine, creatinine, etc.

Enzyme sensor with a cover membrane layer covered by a hydrophilic polymer

A membrane for a sensor, a method for the preparation thereof, a layered membrane structure and a sensor for analytical measurements which require controlled analyte permeability. The membrane, layered structure and sensor may be used for biological, physiological and chemical measurements, however, are especially applicable for electrochemical measurements of glucose, lactate, urea and creatinine. The membrane comprises at least one polymer material, at least one surfactant, and at least one hydrophilic compound in admixture to provide a membrane structure in which micelles of hydrophilic compound lined with thin layers of surfactant are randomly distributed in the bulk polymer of the membrane. Upon conditioning of the membrane a structure of a perculating network of pores lined with surfactant is formed which has excellent permeability properties. The membrane has the additional advantage of a proper adhesion to polymer encapsulant structures. The membrane is prepared from a mixture of at least one polymer material, at least one surfactant, at least one hydrophilic compound and at least one solvent.

Sensor membrane, a method for the preparation thereof, a sensor and a layered membrane structure for such sensor

In a sensor for measuring an analyte in a biological sample whose measuring surface is covered by or comprises a membrane, the membrane has free groups on the surface facing the sample. The surface is modified such that a hydrophilic component is immobilized on the surface in such a manner that chains of the hydrophilic component are chemically bonded to free groups on the surface. Thus, the surface is provided with a more hydrophilic character relative to its unmodified state.

Sensor and membrane for a sensor

Cardable hydrophobic polyolefin fibres comprising cationic spin finishes

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Lynge, Denmark

Lydia Dahl Clausen