Nexttec Gmbh

Lutz Plobner

Robert-Matthias Leiser

Gottfried Brem

Vitali Pavlovich Zubov

Hamlet Balayan

Dmitry Valerievich Kapustin

Elena Jurievna Yagudaeva

Dimitri Valerjewich Kapoustine

Leonti E Tkachenko

Elena Markovna Yaroshevskaya

The present invention relates to a sorbent material for separation and purification of biopolymers, particularly nucleic acids, having a solid support substantially modified with a copolymer coating comprising aromatic monomers and crosslinking compounds and unsaturated esters or ethers preferably attached to the support via a vinylchlorsilane. The use of these materials for separation of nucleic acids, particularly a one-step isolation of DNA from lysates of different biological sources, is an object of the invention as well as a chromatographic column or cartridge at least partially filled with the sorbent material of the invention, a membrane-like device comprising the sorbent material of the invention, and a kit comprising the sorbent material of the invention in bulk or packed in chromatographic devices as well as other devices necessary for performing sample preparations.

Process for manufacturing a composite sorbent material for chromatographical separation of biopolymers

A composite polymer-coated sorbent with a bidisperse or oligodisperse distribution of pore sizes and having an at least partial coating on its surface, which coating comprises essentially polyanilines or derivatives of polyanilines and use thereof for the simultaneous separation and desalting of bio-macromolecules.

Composite polymer-coated sorbent with a bidisperse pore size distribution for the simultaneous separation and desalting of biopolymers

Use of a composite sorbent having an at least partial coating on a support, which coating comprises essentially polyanilines or derivatives of polyanilines for the separation, isolation, identification, purification and/or detection of biomolecules in particular nucleic acids, proteins, polysaccharides in analytical or preparative scale.

Use of a composite polymer-coated sorbent for separation, purification, desalting and concentration of biopolymers

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Erkrath, Germany

Lutz Plobner