Dsm IP Assets B.v.

Gist-brocades B.v.

Cosmoferm B.v.

Dsm N.v.

Novozymes A/s

Basf Aktiengesellschaft

Luppo Edens

Andre Leonardus De Roos

Petrus Jacobus Theodorus Dekker

Joris Kloek

Robertus Antonius Mijndert Van Der Hoeven

Michel Lopez

Alexander Lucia Leonardus Duchateau

Albertus Alard Van Dijk

Maaike Johanna Bruins

Alexander Duchateau

Maximiliaan Peter Marie De Swaaf

Veronique Delest

Andre L Ross De

Rudolf Franciscus Van Beckhoven

Helena Maria Nan

Johanna Plijter-Schuddemat

Hong Sheng Tan

Johannes Wilhelmus Lambers

Wilbert Herman Marie Heijne

Bertus Noordam

Arie Cornelis Schoenmaker

Igor Galaev

Jan Gerrit Kortes

Dieter Maier

Fabio Spreafico

Christian Wagner

Johanna Henrica Gerdina Maria Mutsaers

Aida Hiseni

Ulrike Folkers

Wolfram Kemmner

Kaj Albermann

Alexander Stock

Andreas Fritz

Richard Albang

Oliver Heinrich

Hugo Streekstra

Linda De Lange

Pieter Marinus Van Den Broecke

Thierry Jean-Bernard Naeye

Sylvia Hopper

Olaf Leonardus Schouten

Paul William Schuurhuizen

Cinderella Christina Gerhardt

Andre De Roos

Philippus Antonius Deen

Franciscus Kleinherenbrink

Rudolf Beckhoven Van

Lucas Cyril Gerard Van Der Heyden

Arjen Bot

Lucas Johannes Cornelis Van Loon

Antonius Johannes Maria Wagenmakers

Albertus Van Dijk

Philipp Krubasik

Erik Kimpel

Sabine Klugbauer

Cinderalla C Gerhardt

Wilk Von Gustedt

Pamela Tan

Melissa Harvey

Josephine Stiebler

Jean Marie Lefevre

Arthur Louis Maria Simonetti

Rudolf Van Beck-hoven

Petrus Andreas Van Paridon

Dirk Meijer

Minh-Tam Nguyen

Jeroen Louis Van Roon

Van Jeroen Louis Roon

Van Den Pieter Marinus Broecke

De Andre Leonardus Roos

Rudolf Franciscus W M Van Beckhoven

Lopez Michel

De Maximiliaan Peter Marie Swaaf

Van Albertus Alard Dijk

Franciscus Antonius M Kleinherenbrink

Andre Leonardus Roos

Van Rudolf Franciscus Wilhelmus C Beckhoven

The present invention describes a intracellular produced lactase, which comprises less than 40 units arylsulfatase activity per NLU of lactase activity. The invention also provides a process comprising treating a substrate with an enzyme preparation, wherein the enzyme preparation is substantially free from arylsulfatase.

Enzyme preparations yielding a clean taste

This invention relates to a medicament or a dietary supplement comprising theaspergilloglutamic peptidase that is capable of hydrolyzing plant food allergens, and more particularly, alpha-amylase/trypsin inhibitors, thereby treating diseases due to an innate immune response in humans, and/or allowing to delay the onset of said diseases. The present invention relates to the discovery that theaspergilloglutamic peptidase is capable of hydrolyzing alpha-amylase/trypsin inhibitors that are present in wheat and related cereals said inhibitors being strong inducers of innate immune response. Furthermore, the present invention relates to a method for hydrolyzing alpha-amylase/trypsin inhibitors comprising incubating a composition for food consumption comprising alpha-amylase/trypsin inhibitors with theaspergilloglutamic peptidase, wherein the inhibitors are hydrolyzed. It also relates to an enzyme composition comprising theaspergilloglutamic peptidase and an additional enzyme, and to foodstuff comprising theaspergilloglutamic peptidase.

Medicament and method for treating innate immune response diseases

The present invention relates to immobilized proline-specific endoprotease, wherein the proline-specific endoprotease is immobilized on a carrier comprising methacrylate which has been functionalized with amino dimethylene, and wherein the carrier has a particle size range of 100 to 400 &#x3bc;m. The invention also relates to a process for producing beer comprising the steps of preparing a mash, fermenting the beer, and stabilizing the beer, wherein the beer is incubated with the immobilized proline-specific endoprotease.

Immobilized Proline-specific endoprotease

An edible composition comprising peptides rich in tryptophan, which edible composition further comprises a rapidly available glucose composition and a slowly available glucose composition.

Compositions comprising carbohydrates and peptides which comprise tryptophan

The present invention relates to a process to produce a composition comprising water-soluble peptides and having a Trp/LNAA ratio of more than 0.15, which comprises hydrolyzing lysozyme, preferably hen eggs lysozyme, to prepare a hydrolysate having a DH of between 5 and 45.

Methods of treatment using water-soluble tryptophan-containing peptides obtained by the hydrolysis of hens eggs lysozyme

This invention relates to the use of theaspergilloglutamic peptidase in a feed composition containing cereals, pulses, oilseeds, and/or tubers to improve animal performance, reduce nitrogen excretion and/or reduce intestinal inflammation. Furthermore, the present invention relates to a feed composition or a feed additive comprising theaspergilloglutamic peptidase. The present invention relates to the discovery that theaspergilloglutamic peptidase is capable of efficiently hydrolyzing alpha-amylase/trypsin inhibitors that are present in wheat, barley and related cereal species, as well as hydrolyzing trypsin inhibitors that are present in pulses, oilseeds, and tubers. Furthermore, the present invention relates to a method of improving animal performance comprising improving feed conversion ratio, and/or improving daily weight gain, and/or reducing intestinal inflammation, and/or reducing nitrogen excretion in an animal fed a feed stuff containing alpha-amylase and/or trypsin inhibitors, comprising orally administering a sufficient amount of theaspergilloglutamic peptidase. It also relates to the pretreatment of feedstuff with theaspergilloglutamic peptidase.

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The present disclosure relates to a composition, and method thereof, which comprises tryptophan whereby 10 to 90%, preferably 20 to 80% of the tryptophan is present as free tryptophan or peptide-bound tryptophan and 10 to 90%, preferably 20 to 80% of the tryptophan is present as polypeptide-bound tryptophan.

Process to produce a tryptophan-enriched lysozyme hydrolysate

Process for producing a dairy product by adding a lactase to a dairy product which contains lactose, the lactase added having less than 40 units arylsulfatase activity per NLU of lactase activity.

A process to prepare packaged pasteurized or sterilized aqueous drinkable products which comprise casein micelles (e.g. from dairy protein) and peptide-fractions, which peptide fractions are rich in tryptophan, and the products so-obtained. The process requires a heat preservation at a specific pH.

Process for the preparation of packaged heat-preserved aqueous drink comprising casein micelles and tryptophan-rich peptides, and product so obtained

The present invention relates to a composition which comprises tryptophan whereby 10 to 90%, preferably 20 to 80% of the tryptophan is present as free tryptophan or peptide-bound tryptophan and 10 to 90%, preferably 20 to 80% of the tryptophan is present as polypeptide-bound tryptophan.

Mixture of peptide-bound tryptophan and polypeptide-bound tryptophan

The present invention relates to a process for the proteolytic hydrolysis of a peptide or a polypeptide, said peptide or polypeptide comprising 4 to 40, preferably 5 to 35, amino acid residues and said peptide or polypeptide is not hydrolysable by subtilisin whereby said peptide or polypeptide is hydrolysed by a proline specific endo protease at a pH of 6.5 or lower, preferably 5.5 or lower and more preferably 5.0 or lower to hydrolyse said peptide or polypeptide.

Use of proline specific endoproteases to hydrolyse peptides and proteins

The invention relates to a method for the prevention or reduction of haze in a beverage by the addition of a prolyl-specific and/or alamine specific endoprotease and the new beverages obtainable by the method according to the invention. It also relates to new endoproteases. It also relates to methods as described above wherein auxiliary enzymes are used in combination with the specific endoprotease. Sequence information of a genomic DNA, cDNA as well as protein sequences are provided.

Method for the prevention or reduction of haze in beverages

The invention relates to a method for the prevention or reduction of haze in a beverage by the addition of an prolyl-specific endoprotease and to new beverages obtainable by the method according to the invention. It also relates to new endoproteases. Sequence information of a genomic DNA, cDNA as well as protein sequences.

A process to produce IPP from a protein source whereby the protein source comprises a protein having the -I-P-P- sequence and having in the protein amino acid sequence at least 6 times more -I-P-P- present than -V-P-P- (molar basis) which comprises hydrolysing the protein source to liberate at least 40% of the I-P-P- sequence into the peptide IPP and whereby a proteolytic enzyme is used which cleaves at the carboxy-terminus of proline residues present in the protein source, the enzyme is preferably a proline specific endoprotease or proline specific oligopeptidase, more preferably a proline specific endoprotease, and optionally an amino peptidase.

Blood pressure lowering peptides from glycomacropeptide

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Rotterdam, Netherlands

Luppo Edens