3m Innovative Properties Company

Luke T Dressel

Joseph F Dellaria, Jr

Doris Stoermer

Matthew R Radmer

Kyle J Lindstrom

Bernhard M Zimmermann

David T Amos

Jason D Bonk

Philip D Heppner

John R Jacobsen

William H Moser

Joan T Moseman

Miguel Antonio Guerra

Tatsuo Fukushi

Marvin E Jones

Terence D Spawn

Fuming B Li

Steven J Martin

Daniel A Japuntich

John M Sebastian

James Arthur McDonell

Daniel E Duffy

Aaron E Hutt

Eric A Schotz

Jeremy A Miller

Christopher M Geise

James A Mcdonell

Joseph F Dellaria

Imidazo-quinoline, -pyridine, and -naphthyridine ring systems (particularly quinolines, tetrahydroquinolines, pyridines, [1,5]naphthyridines, [1,5]tetrahydronaphthyridines) substituted at the 1-position with a cyclic substituent, pharmaceutical compositions containing the compounds, methods of making these compounds, and methods of use of these compounds as immunomodulators, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.

Substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines

A method of making &#x3b1;,&#x3c9;-diiodoperfluoroalkanes includes combining: diatomic iodine, at least one perfluoroalkylene oxide represented by the formula wherein Rrepresents a perfluoroalkyl group; and at least one of: a) a first metallic compound comprising nickel, and a second metallic compound comprising molybdenum that is compositionally different from the first metallic compound; or b) a metallic alloy comprising from 50 to 70 percent by weight of nickel and from 20 to 40 percent by weight of molybdenum, based on the total weight of the metallic alloy, thereby producing at least one product represented by the formula I(CF)I, wherein n independently represents an integer in the range of from 1 to 11. The total weight of the at least one product wherein n is 3 or greater exceeds the total weight of the at least one product wherein n is 1 or 2 by a factor of at least 4. 

Method of making alpha, omega-diiodoperfluoroalkanes

Electret webs are presented which include a blend of a thermoplastic resin and a charge additive. The charge additives include ester-substituted and amide-substituted trianilino triazine materials. The webs prepared from the blends may be in the form of films or non-woven fibrous webs. Non-woven microfiber webs are useful as filtration media.

Electret webs with charge-enhancing additives

Imidazopyridine compounds that contain an ether or thioether functionality at the 1-position are useful as immune response modifiers. The compounds and compositions of the invention can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases. Methods of preparing the compounds and intermediates useful in the preparation of the compounds are also disclosed.

Ether substituted imidazopyridines

A process and intermediates for preparing 1H-imidazo[4,5-c]pyridin-4-amines are disclosed. The process includes providing a 7H-imidazo[4,5-c]tetrazolo[1,5-a]pyridine and converting a 7H-imidazo[4,5-c]tetrazolo[1,5-a]pyridine to a 1H-imidazo[4,5-c]pyridin-4-amine.

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A process and intermediates for preparing 1H-imidazo[4,5-c]pyridin-4-amines are disclosed. The process includes providing a 7H-imidazo[4,5-c]tetrazolo[1,5-&#x3b1;]pyridine and converting a 7H-imidazo[4,5-c]tetrazolo[1,5-&#x3b1;]pyridine to a 1H-imidazo[4,5-c]pyridin-4-amine.

Process for imidazo[4,5-c]pyridin-4-amines

A process and intermediates for preparing 1H-imidazo&lsqb;4,5-c&rsqb;pyridin-4-amines are disclosed. The process includes providing a 4-phenoxy-1H-imidazo&lsqb;4,5-c&rsqb;pyridine and aminating the 4-phenoxy-1H-imidazo&lsqb;4,5-c&rsqb;pyridine to provide a 1H-imidazo&lsqb;4,5-c&rsqb;pyridin-4-amine.

Process for imidazo&lsqb;4,5-c&rsqb;pyridin-4-amines

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Somerset, WI, United States of America

Luke T Dressel