Merck Sharp + Dohme Corp.

Other

Luke Fire

Joseph A Kozlowski

Wensheng Yu

Ling Tong

Dansu Li

Bandarpalle B Shankar

Brian J Lavey

Michael K C Wong

Seong Heon Kim

Guowei Zhou

De-Yi Yang

Razia Rizvi

Judson E Richard

Lei Chen

Kristin E Rosner

Aneta Maria Kosinski

M Arshad Siddiqui

Janeta Popovici-Muller

Vinay M Girijavallabhan

Chaoyang Dai

Liping Yang

Robert Feltz

Aneta Maria Kosinzki

Kristen E Rosner

Razia K Rizvi

This invention relates to compounds of the Formula (I) as described herein, or a pharmaceutically acceptable salt, solvate or ester thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF- or combinations thereof. 

Compounds for the treatment of inflammatory disorders

This invention relates to compounds of the Formula (I): (Chemical formula should be inserted here as it appears on abstract in paper form) (I) or a pharmaceutically acceptable salt thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF- or combinations thereof. 

This invention relates to compounds of the Formula (I): (Chemical formula should be inserted here as it appears on abstract in paper form) (I) or a pharmaceutically acceptable salt, solvate or isomer thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF&#x2014;or combinations thereof. 

This invention relates to compounds of the Formula (I)-(IX):, as defined herein, or a pharmaceutically acceptable salt, solvate or ester thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF-&#x3b1; combinations thereof. 

Compounds for the treatment of inflammatory diseases

Growing community of inventors

Cambridge, MA, United States of America

Luke Fire