Roche Molecular Systems, Inc.

Muller Martini Holding Ag

Roche Diagnostics Gmbh

F. Hoffmann-la Roche Ag

Lukas Dysli

Christian Thalmann

Andreas Flück

Daniel Graber

The present disclosure relates to an analytical system with at least three components: a multiwell plate on which the wells are included in an optically transparent area; a frame holding the multiwell plate close to its edge while permitting the plate a certain extent of freedom of movement; a baseplate to which the multiwell plate, but not the frame is firmly fixed via a docking mechanism, such that different expansion of plate and frame can be compensated. A second aspect described herein relates to a method of docking a corresponding multiwell plate held by a frame to a baseplate and subjecting the multiwell plate to a step of a biological or chemical assay within this arrangement.

Analytical system with accurate positioning of multiwell plates

A method and device for stitching printed products with a stitching machine, which includes a stitcher head and a bending device, which travel concomitantly with each printed product as it is conveyed in a travel direction during the stitching operation. The bending device is positioned first in a first position, which corresponds to the thickness of the printed products and is a certain distance away from the stitcher head in the direction transverse to the travel direction. Before a printed product is introduced, its thickness is determined and compared with a predetermined limit value; and, if this limit value is exceeded, the bending device is brought into a predetermined second position, which is farther away than the first position from the stitching head. After the printed product has been introduced, the bending device is moved back into the first position, and the wire stitch is driven into the printed product.

Stitcher for variable thickness products

Growing community of inventors

Aarau, Switzerland

Lukas Dysli