Coretech Medical Technologies Corporation

Other

National Research Council of Canada

University of Manitoba

Luis Oppenheimer

Henry H Mantsch

David Hugh Burns

Michael G Sowa

Lorenzo Leonardi

Jing Wang

Pulmonary edema in the lung is detected by exposing a lung under investigation to infrared radiation, especially near-infrared radiation; measuring the reflected radiation scattered by the lung as a spectral response to the presence of water in the lung; comparing the reflected radiation with calibrated values and evaluating occurrence of pulmonary edema from the comparison.

Diagnosis of edema

A spectrophotometric analytical method for lung permeability is described. An exogenous polydispersed macromolecule is administered, and fluid of the patient is evaluated using infrared spectroscopy.

Lung permeability analysis

A spectrophotometric method and device are described which are particularly useful for on-line monitoring and control of blood parameters. Determination of a blood parameter without measuring or directly following another blood parameter, is made possible by using information contained in scatter and at least three distinct detection locations. Calibration using means for scattering a light beam to a suitable reference geometry, is beneficially used. Constant values related to the detection locations are derived. Later, these constants may be used to determine a blood parameter. Two different wavelengths and at least for detectors may be used. The device is beneficially applied to extracorporeal circuits, and may be used to optimize dialysis.

Spectrophotometric blood analysis

A method and device are described which are particularly useful for continuous on-line monitoring of hematocrit and other blood parameters. The effect of change in blood electrolyte composition, for example, in blood sodium concentration, is taken into consideration. This effect has been found to change light beam geometry, and is taken advantage of to provide for blood sodium concentration measurement. The devices may be applied to extracorporeal circuits or to body parts capable of being transilluminated. The devices may be used to optimize dialysis, and also for monitoring optically detectable, exogenous macromolecules.

Growing community of inventors

Winnipeg, Canada

Luis Oppenheimer