Danisco US Inc.

The Procter Gamble Company

Danisco US Inc., Genencor Division

Luis Gustavo Cascao-Pereira

David Aaron Estell

James T Kellis, Jr

Ayrookaran J Poulose

Joshua Roy Basler

Philip Frank Souter

Glenn Steven Ward

Alexander Pisarchik

Clement K Choy

Brian E Jones

Scott Douglas Power

Marc Kolkman

Walter Weyler

Bradley R Kelemen

Thijs Kaper

Sandra W Ramer

Melodie Estabrook

William Albert Cuevas

Louise Wallace

Viktor Alekseyev

Claudine Chang

Daniel Esteban Torres-Pazmino

Amr R Toppozada

Amy D Liu

Frits Goedegebuur

Jian Yao

Katherine D Collier

Neelam S Amin

Richard Ray Bott

Andrew Shaw

Jayarama K Shetty

Katherine Augustyn

Wolfgang Aehle

Michael Jay Pepsin

Vivek Sharma

Chris Leeflang

Sang-Kyu Lee

Casper Vroemen

Brian Frederick Schmidt

Harm Jan Mulder

Donald E Ward

Carol A Requadt

Euan John Magennis

Edward M Concar

Casper Willem Vroemen

David E Wildes

Regina Chin

Casper Vroeman

Dina Finan

Ayrookaran J Poulouse

Phillip Frank Souter

Ayrookaran J Poulise

Marc Koklman

Jr James T Kellis

Viktor Yuryevich Alekseyev

James T Kellis Jr

James T Kellis

Bradley Paulson

Ayrookaran Joseph Poulose

Dewy Van Tol

Jr Kellis James T

William A Cuevas

Marc Kolman

Daniel Torres-Pazmino

Viktor Yurevich Alekseyev

Pieter Augustinus

Monica Ocha Ruiz

Harm Mulder

David A Estell

Jr Kellis

Jashua Roy Basler

This invention relates to fabric and home care products comprising one or more cold water proteases and processes for making and using such products. Such compositions provide improved cleaning and freshness. Such cold water proteases may be derived from parent enzymes, including BPN' subtilisin and subtilisin derived from, by substitution, insertion and/or deletion of one or more of the parent enzymes' amino acids.

Fabric and home care products with cold water protease

The present invention provides serine protease variants produced there from. Specifically, the present invention provides serine protease variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants.

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Fabric and home care products comprising cold water proteases

The present invention provides variant subtilisins and compositions comprising at least one variant subtilisin set forth herein, as well as methods for using these variants and compositions. In some embodiments, the present invention provides variant subtilisins suitable for laundry cleaning applications.

Compositions and methods comprising variant microbial proteases

Disclosed are compositions and methods relating to variant maltohexaose-forming alpha-amylases. The variant alpha-amylases are useful, for example, for starch liquefaction and saccharification, for cleaning starchy stains in laundry, dishwashing, and other applications, for textile processing (e.g., desizing), in animal feed for improving digestibility, and for baking and brewing.

Variant maltohexaose-forming alpha-amylase variants

The present invention provides methods for protein engineering and serine protease variants produced there from. Specifically, the present invention provides serine protease variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants.

Compositions and methods comprising serine protease variants

The present invention provides serine protease variants, more specifically subtilisin variants produced there from. Specifically, the present invention provides serine protease variants, more specifically subtilisin variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants, more specifically subtilisin variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants, more specifically subtilisin variants.

The present disclosure relates to cellulase variants. In particular the present disclosure relates to cellulase variants having reduced binding to non-cellulosic materials. Also described are nucleic acids encoding the cellulase, compositions comprising said cellulase, methods of identifying cellulose variants and methods of using the compositions.

Compositions and methods comprising cellulase variants with reduced affinity to non-cellulosic materials

The present invention provides protease variants, compositions comprising protease variants, and methods of using such protease variants and compositions.

Methods for cleaning using a variant protease derived from subtilisin

The present invention provides efficient methods for obtaining a protein with one or more beneficial attributes in industrial, consumer or pharmaceutical applications. In some preferred embodiments, the present invention provides methods for producing superior enzymes for a given application through screening an abbreviated set of candidate enzymes.

Methods for improving multiple protein properties

The present invention provides engineered protease variants. In particular, the protease variants comprise combinable mutations at selected surface positions that affect the charge and/or hydrophobicity of the enzyme to enhance at least one desired property of the resulting variant enzyme in a chosen application. Compositions comprising the protease variants, and methods for using the same are also provided.

Proteases comprising one or more combinable mutations

An &#x3b1;-amylase from(AmyE) produces significant amounts of glucose from various carbohydrate substrates, including vegetable starch, maltoheptaose, and maltotriose. Among other things, this advantageous property allows AmyE or variants thereof to be used in a saccharification reaction having a reduced or eliminated requirement for glucoamylase. The reduction or elimination of the glucoamylase requirement significantly improves the efficiency of the production of ethanol or high fructose corn syrup, for example.

Alpha-amylases from(AmyE), variants thereof, nucleic acids encoding the same, and host cells comprising the nucleic acids are provided. Methods of using AmyE or variants thereof are disclosed, including liquefaction and/or saccharification of starch. Such methods may yield sugars useful for ethanol production or high fructose corn syrup production. In some cases, the amylases can be used at low pH, in the absence of calcium, and/or in the absence of a glucoamylase.

Described are variants (mutants) of a parent alpha-amylase having alpha-amylase activity and exhibiting altered properties relative to the parent alpha-amylase, and methods of use, thereof.

TS-23 alpha-amylase variants with altered properties

Growing community of inventors

Redwood City, CA, United States of America

Luis Gustavo Cascao-Pereira