Abraxis, Inc.

Centre National De La Recherche Scientifique

Institut Pasteur

Centre National De La Recherche Scientifique-cnrs

Universidad De Santiago De Compostela

Luis Botana

Jordi Molgo

Hoang-Oanh Nghiem

Romulo Araoz

Natalia Vilarino

The pr&#xe9;sent invention relates to a method for manufacturing an analysis device including torp&#xe9;do membrane fragments immobilized at the surface thereof, to the resulting analysis device, and to the use of said device for detecting, purifying, and characterizing mol&#xe9;cules acting on nicotinic acetylcholine receptors. The pr&#xe9;sent invention is useful in the field of monitoring seafood, monitoring neurotoxic phytoplankton for the shellfish industry, monitoring the quality of bathing waters along tourist beaches, the field of monitoring fresh water reserves, the field of m&#xe9;dical research, the field of the biological analysis and characterization of mol&#xe9;cules, e.g., non-radioactive assays of the movement of the ligand-receptor bond on an ELISA-type microplate, thereby enabling comp&#xe9;titive agonists and antagonists of targets to be detected, e.g., of highly sensitive receptors.

Method for manufacturing an analysis substrate, and use thereof for detecting toxins

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Luis Botana