Dr. L. Zambeletti Spa

Dr. Lo. Zambeletti S.p.a.

Zambeletti Espana, S.a.

Dr. L. .degree. Zambeletti S.p.a.

Luigi Molteni

Massimo Signorini

Eraldo Antonini

Franco Bolasco

Adriana Memoli

Claudio Botre

Jose A Ramirez Fernandez

Franco Montrone

Franco Scrollini

Innocenzo Caruso

Gian Piero Vercesi

Giampiero Vercesi

Attilio Trebbi

A process for preparing 1-(3,5-dimethoxy-4-hydroxy phenyl)-2-(N-methylamino) ethanol hydrochloride is described by reacting 2,6-dimethoxyphenol with anhydrous chloral in the presence of a catalyst, hydrolyzing 1-(3,5-dimethoxy-4-hydroxyphenyl)2,2,2-trichloro ethanol and subsequently isolating the 3,5-dimethoxy-4-hydroxyphenyl glyoxal thus obtained; finally, this compound, in the form of the bisulfite, is directly converted to the desired product by amination with methylamine in the presence of hydrogen with a hydrogenation catalyst and the final product is converted into the hydrochloride.

Process for preparing 1-(3,5-dimethoxy-4-hydroxy

The invention concerns new salts of rifamycin SV and a new use of rifamycin SV in the treatment of rheumatoid arthritis and analogous affections, by intra-articular injection of the sodium salt of rifamycin SV or, better, of salts of said anti-biotic with basic aminoacid, e.g. with arginine, lysine or histidine.

Use of rifamycin SV and its related salts in the treatment of rheumatoid

This invention provides an iodinated derivative of benzalkonium chloride having antiseptic activity combined with a lower toxicity than the corresponding chloride.

Compound with disinfectant activity and pharmaceutical compositions

Pyridoxin derivatives of the general formula: ##STR1## wherein Y is described herein for use as antineuritics and analgesic drugs.

Pyridoxylidine amino benzoate compounds

This invention relates to aseries of tripeptides of the general formula: ##STR1## wherein R = -- H, COCH.sub.3, alkyl

Tripeptides, their esters and amides, and anti-ulcera activity thereof

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Malnate, Italy

Luigi Molteni