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Stembios Technologies, Inc.

Lufen Chang

James Han Wang

Yun Yen

James Wang

Disclosed are methods of using blastomere-like stem cells to decrease a level of myeloid-derived suppressor cells (MDSCs). A method for decreasing a level of myeloid-derived suppressor cells (MDSCs) in a human subject, including: injectionally, orally or transdermally administering to the human subject an amount of human blastomere-like stem cells, autologous to the human subject, at 1&#xd7;10to 1&#xd7;10cells each time once every two weeks, for example.

Treatment of immunosuppression-related disorders

Disclosed are methods of using blastomere-like stem cells to (1) decrease the level of myeloid-derived suppressor cells, (2) modulate immune response, (3) overcome a myeloid-derived suppressor cell-mediated immunosuppression, and (4) treat a cellular proliferative disorder. The blastomere-like stem cells, positive for CD66e, can be isolated from blood, bone marrow, or skeletal muscle.

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Monterey Park, CA, United States of America

Lufen Chang