Biochemie Gesellschaft M.b.h

Ludwig Miller

Johannes Ludescher

Hubert Sturm

Siegfried Wolf

Werner Veit

Martin Decristoforo

Crystalline 2-(amninothiazol-4-yl)-2-(tert.butoxycarbonylmethoxyimino)acetic acid-S-mercapto-benzo-thiazolylester in form of an N,N-dimethylacetamide solvate; a crystalline salt of a 7-&lsqb;2-(aminothiazol-4-yl)-2-(carboxymethoxyimino)acetamido&rsqb;-3-vinyl-3-cephem-4-carboxylic acid with an amine of formula N(R,)(R,)(R,), wherein R,, R,, and R,have various meanings, a crystalline sulphuric acid addition salt of a 7-&lsqb;2-(2-aminothiazol-4-yl)-2-carboxymethoxyimino)acetamido&rsqb;-3-vinyl-3-cephem-4-carboxylic acid; and the use of these salts in the production of cefixime, e.g. in form of a trihydrate.

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Ludwig Miller