Basf Aktiengesellschaft

Ludwig Friedrich

Dieter Lenke

Josef Gries

Albrecht Franke

Marco Thyes

Hans D Lehmann

Gerd Steiner

Manfred Raschack

Horst Koenig

Rainer Schlecker

Claus D Mueller

Frank Zimmermann

Peter Neumann

Heinz Eilingsfeld

Guenther Seybold

Werner Seitz

Hans P Hofmann

Fritz-Frieder Frickel

Horst Kreiskott

Phillip A Rossy

Rolf Kretzschmar

Hans J Treiber

Wolfram Frank

Bernd Ostersehlt

Fritz Binnig

Hans P Albrecht

Ferdinand Dengel

Oskar Ehrmann

Hans-Georg Kurbjuweit

Dirk Wuppermann

Philip A Rossy

Novel 6-(acylaminaryl)-3(2H)-pyridazinones of the formula ##STR1## where R.sup.1, R.sup.2, R.sup.3, R.sup.4, A and B have the meanings given in the description, and their preparation are described. The compounds have thrombocyte aggregation-inhibiting activity.

6-(acylaminoaryl)-3(2H)-pyridazinone derivatives, and their use

Novel 6-(acylaminoaryl)-3(2H)-pyridazinones of the formula ##STR1## where R.sup.1, R.sup.2, R.sup.3, R.sup.4, A and B have the meanings given in the description, and their preparation are described and inhibiting thrombocyte aggregation and gastric secretion. The compounds are useful for treating disorders.

6-(acylaminoaryl)-3(2H)-pyridazinone derivatives and their use

Thiazolyloxamic acids and their derivatives of the general formula I ##STR1## processes for their preparation, and pharmaceutical formulations which contain these compounds and are useful as drugs for treating allergic disorders.

Tricyclic thiazolyloxamic acids and their derivatives, their

N-substituted imidazole derivatives of the formula I ##STR1## where R.sup.1, R.sup.2 and R.sup.3 are identical or different and are each hydrogen or alkyl with 1 or 3 carbon atoms and Alk is an alkylene chain of 2 to 4 carbon atoms, and their salts with physiologically tolerated acids, processes for their preparation, drugs containing a compound of the formula I or one of its salts, and their use for treating disorders associated with gastric hyperacidity.

Gastric acid secretion inhibiting N-(imidazol-1-ylalkyl)thiourea

5,6-Dihydro-11-methylenemorphanthridin-6-ones of the formula I ##STR1## where R.sup.1, R.sup.2, R.sup.3 and R.sup.4 have the meanings given in the description, and their preparation and use. The novel substances are particularly useful for treating gastric and duodenal ulcers.

5,6-Dihydro-11-methylenemorphanthridin-6-ones, their preparation and

1,2,4-Triazolo[1,5-c]-quinazolinones of the general formula I ##STR1## and their pharmaceutically tolerated salts, processes for their preparation and pharmaceutical formulations which contain these compounds and are useful drugs in the treatment of allergic disorders.

Triazoloquinazolinones, and compositions and methods for treating

.omega.-Cyano-1,.omega.-diphenyl-azaalkane derivatives of the formula I ##STR1## where R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, R.sup.8, m and n have the meanings given in the description, and salts thereof with physiologically tolerated acids, are useful in treating cardiovascular disorders.

.OMEGA.-Cyano-1, .OMEGA.-diphenyl-azaalkane derivatives, their

Novel 2-substituted thiazol-2-yl-oxamic acid esters, processes for their preparation, and therapeutic agents which contain these compounds and are useful in the treatment of allergic disorders.

Thiazol-2-yl-oxamic acid derivatives, and therapeutic agents containing

Novel 5,6-dihydro-11-alkylene-morphanthridin-6-ones of the formula ##STR1## where R.sup.1, R.sup.2, R.sup.3 and R.sup.4 have the meanings given in the description, their preparation and their use. The novel compounds are particularly useful in the treatment of gastric and duodenal ulcers.

5,6-Dihydro-11-alkylene-morphanthridin-6-ones, their pharmaceutical

Bispidine derivatives of the formula ##STR1## where R.sup.1 is H or C.sub.6 H.sub.5, R.sup.2 is H, Cl or CF.sub.3, R.sup.3 is H, F or Cl and X is 0 or 1, and drugs which contain these compounds. The compounds are prepared by condensing N-monobenzylbispidine with appropriately substituted phenylethyl halides or by a Mannich reaction of N-benzylpiperid-4-one with appropriately substituted phenylalkylamines, followed by reduction. They exhibit mainly anti-arrhythmic action.

Bispidine derivatives, their preparation, and drugs containing same

Hypolipemic non-glycosidic theophylline-sugar compounds having the formula ##STR1## are disclosed, as are a method for making them and methods and compositions for treating hyperlipemia with the compounds.

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Bruehl, Germany

Ludwig Friedrich