Vifor Fresenius Medical Care Renal Pharma Ltd.

Shl Medical Ag

Weibel Cds Ag

Vifor (international) Ag

Actelion Pharmaceuticals Ltd

Idorsia Pharmaceuticals Ltd

Vifor Ag

Ludwig Daniel Weibel

Erik Philipp

Samuel Wyler

Christoph Egloff

Philippe Kern

Gallus Egli

Peter Kuhn

Mario Schüpbach

Mario Schuepbach

A primary packaging for a liquid including an at least partially collapsible container and a connector element for connection of the primary packaging to a withdrawal device. The connector element has at least one connector channel which is in fluid communication with an interior space of the container. The container is composed at least partially of a foil which is constructed from a first layer which, during intended use of the primary packaging comes into direct contact with the liquid. Both the first layer and the connector element are composed of a plastics material including at least one cyclic olefin polymer.

Primary packaging

A device () for dispensing a substance to a patient comprising a cylindrical first container () containing the substance and a second container () containing a liquid. The device further comprises an injection device () and transfer mechanism () for transferring the liquid from the second container () to the first container () and from the first container () to the injection device (). The first container () has a connection element () and a plunger () that can be moved between the first () and second ends (). By moving the plunger () towards the first end (), liquid contained therein can be dispensed via the injection device (). The injection device () comprises a piercing cannula () and an indwelling cannula (). In an initial position, a distal end region of the piercing cannula () extends coaxially in the interior of the indwelling cannula ().

Device for dispensing a substance

A device () for dispensing a fluid, in particular under aseptic conditions, preferably to a patient. The device comprises a conveying device () for conveying the fluid to a dispensing opening (). The device () also comprises a coupling element () for coupling a syringe (). The fluid can be conveyed from the syringe () to the dispensing opening () via the coupling element () and the conveying device () exclusively by the effect of the conveying device (). The invention further relates to a system for dispensing a fluid under aseptic conditions, comprising such a device () and to a syringe () that can be coupled to the coupling element ().

Device and system for dispensing a fluid under aseptic conditions

An injection device for subcutaneous delivery of fluid which comprises a puncture cannula and an indwelling cannula. In a starting position, a distal end region of the puncture cannula runs coaxially inside the indwelling cannula. The device comprises displaceably mounted first and second runners. The first runner is connected to the puncture cannula and the second runner to the indwelling cannula. A control element is movable over a predefined control area. The control element is configured such that, in a first part of the control area, the control element effects an equidirectional displacement of the first and the second runners, and hence fitting of the indwelling cannula and, in a second part of the control area, effects blocking of the second runner, and hence holding of the indwelling cannula in a dwell position, and return of the first runner and withdrawal of the puncture cannula into an end position.

Dosing apparatus and injection device

The dosing apparatus comprises a conveying device (), which is driven by at least one conveying drive (), for conveying fluid from the interior () of a container (). The fluid by means of the conveying device () is conveyable from the container to a dispensing opening (). The conveying device () comprises a cylinder () having at least one intake opening () and at least one outlet opening () on an inner cylinder wall (), and a first piston () and a second piston (). The first piston () and the second piston () are mounted within the cylinder () so as to be displaceable in the longitudinal direction. Furthermore, the first piston () and the second piston () between the end sides thereof and together with a portion of the inner cylinder wall () delimit a variable fluid volume ().

Dosing apparatus for dispensing a fluid under aseptic conditions

Pharmaceutical compositions for oral administration, in particular administration as an oral delivery system to be swallowed directly or capable of disintegration in the oral cavity, comprising iron oxy-hydroxide in high loading.

Pharmaceutical compositions

A device () and the use thereof for dispensing fluid under aseptic conditions. The device () comprises conveying device () and container () with a variable inner volume. The conveying device comprises cylinder () with at least three openings () which are arranged along longitudinal central axis (). Displaceable first and second pistons () are arranged in the cylinder. The end faces () of the pistons and inner wall () of the cylinder, delimit a variable fluid volume (). The first opening is brought into fluidic communication with dispensing opening () and the second opening is brought into fluidic communication with the container. Each of the pistons comprise three seals (&#x2033;) which are offset and sealingly close off the cylinder. Adjacent piston seals have inner spacing (di) which is equal to a shortest spacing (aA) between two adjacent openings (or).

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Waldstatt, Switzerland

Ludwig Daniel Weibel