Centre National De La Recherche Scientifique

Pierre Fabre Medicament

Sapienza Universitá Di Roma

Università Degli Studi Di Roma "La Sapienza"

Ludovic Halby

Paola Barbara Arimondo

El Bachir Kaloun

Antonello Mai

Christophe Long

Yoann Menon

Dante Rotili

Paola B Arimondo

Paola Arimondo

The invention concerns a compound of the following formula (I) or a pharmaceutically acceptable salt or solvate thereof as well as a pharmaceutical composition containing such a compound, and the use of such a compound as a drug, notably as a DNMT inhibitor, in particular in the treatment of cancer. 

Hemi-synthetic trilobine analogs for use as a drug

The present invention relates to compounds of the following formula (I) and pharmaceutically acceptable salts and solvates thereof, their methods of preparation, their use as a drug, notably in the treatment of cancer, and pharmaceutical compositions containing such compounds. 

Substituted quinazoline derivatives as DNA methyltransferase inhibitors

The present invention relates to compounds of the following formula (I): and pharmaceutically acceptable salts and solvates thereof, their methods of preparation, their use as a drug, notably in the treatment of cancer, and pharmaceutical compositions containing such compounds. 

Quinazoline derivatives and their use as DNA methyltransferase inhibitors

Growing community of inventors

Toulouse, France

Ludovic Halby