Iowa State University Research Foundation Inc

Omegachea

Ludmila Rizhsky

Basil J Nikolau

Marna Yandeau-Nelson

Shivani Garg

Huanan Jin

Xiaochen Yu

A method of producing bi-functional fatty acids comprising introducing into a host cell or organism, which comprises one or more &#x3c9;- or &#x3c9;-1 functionalized acyl-CoAs, and expressing therein a KASIII, which can use one or more of the &#x3c9;- or &#x3c9;-1 functionalized acyl-CoAs as a substrate; a method of producing a &#x3c9;-1 hydroxy branched fatty acid, a &#x3c9;-1 branched fatty acid, or a combination thereof by culturing a mutant, which does not express a functional KASIII from the endogenous fabH gene and expresses a phaA and a phaB and a functional exogenous KASIII; and a mutant, a method of making the mutant, a culture comprising the mutant, and a composition comprising &#x3c9;-1 hydroxy branched fatty acids, a &#x3c9;-1 branched fatty acids, or a combination thereof obtained from the culture.

Growing community of inventors

Ames, IA, United States of America

Ludmila Rizhsky