Boston Scientific Scimed, Inc.

Boston Scientific Corporation

Prutech Research and Development Partnership Ii

Lucien A Couvillon, Jr

Ian W Hunter

Robert J Crowley

Mark L Adams

Stephen D Fantone

Michael S Banik

John E Abele

William Joseph Shaw

Vincent A Turturro

Dennis R Boulais

Luis J Maseda

Christopher A Rowland

John P O'Connor

Laurence D Brenner

Timothy J Mason

William H Stahley

David W Hoffman

Donald C Hovey

Daniel J Braunstein

Anh Nguyen

Richard J Clark

Patsy A Coppola, Iii

Samuel Sheng-Ping Zhong

Frank J Anderson

Andrew P Kirouac

Neil R Mehta

Anna E R Greaves

Daniel G Orband

Michael Saber

Albert C C Chin

Francis T Macnamara

Richard M Wiseman

A medical device, for example, an endoscope or catheter, includes local drug delivery capabilities for selectively delivering at least one drug in vivo. The local drug delivery may occur as the medical device is advanced through tortuous passageways of the patient's body or may occur after the medical device has reached its targeted destination. The medical device includes a drug agent, for example, carried in or on a hydrophilic or hydrogel coating disposed on the outside thereof. When the hydrogel or drug agent receives an appropriate signal, e.g., solution containing a triggering agent or triggering condition, e.g., heat or light, the hydrogel contracts or expands to squeeze out the drug from hydrogel. If electric current is provided as the signal, and the drug agent is charged, the drug agent is released by electrophoretic forces.

Medical devices with local drug delivery capabilities

In one aspect, the present invention is a system for preparing a patient for an endoscopy procedure, such as a colonoscopy. The endoscopic preparation and examination system includes an endoscope, a source of irrigation and aspiration, and a control unit. The endoscope includes an elongated flexible shaft with a distal tip and a proximal end, at least one aspiration lumen and at least one irrigation lumen. A plurality of irrigation ports are functionally connected to the at least one irrigation lumen and a plurality of aspiration ports are functionally connected to the at least one aspiration lumen. In another aspect, the invention provides a method of clearing an obstructed view in a patient prior to, or during an endoscopic examination.

Device for obstruction removal with specific tip structure

The present invention provides an exterior counterpulsation (ECP) system that includes a garment for being worn on the exterior of a patient's body. The garment includes electroactive polymer (EAP) actuators connected thereto. In one embodiment, the EAP actuators are woven into the garment. In another embodiment, they are mounted to the garment surface.

External counterpulsation device using electroactive polymer actuators

Acoustic imaging balloon catheters formed by a disposable liquid-confining sheath supporting a high fidelity, flexible drive shaft which carries on its end an ultrasound transducer and includes an inflatable dilatation balloon. The shaft and transducer rotate with sufficient speed and fidelity to produce real time images on a T.V. screen. In preferred embodiments, special features that contribute to the high fidelity of the drive shaft include the particular multi-filar construction of concentric, oppositely wound, interfering coils, a pre-loaded torque condition on the coils enhancing their interfering contact, and dynamic loading of the distal end of the probe, preferably with viscous drag. The coil rotating in the presence of liquid in the sheath is used to produce a desirable pressure in the region of the transducer. Numerous selectable catheter sheaths are shown including a sheath with an integral acoustically-transparent window, sheaths with end extensions that aid in positioning, a liquid injection-producing sheath, a sheath having its window section under tension employing an axially loaded bearing, a sheath carrying a dilatation or positioning balloon over the transducer, a sheath carrying a distal rotating surgical tool and a sheath used in conjunction with a side-viewing trocar.

Acousting imaging catheters and the like

Acoustic imaging catheters formed by a disposable liquid-confining sheath supporting a high fidelity, flexible drive shaft which carries on its end an ultrasound transducer. The shaft and transducer rotate with sufficient speed and fidelity to produce real time images on a T.V. screen. Special features that contribute to the high fidelity of the drive shaft include the particular multifilar construction of concentric, oppositely wound, interfering coils, a preloaded torque condition on the coils enhancing their interfering contact, and dynamic loading of the distal end of the probe, preferrably with viscous drag. The coil rotating in the presence of liquid in the sheath is used to produce a desirable pressure in the region of the transducer. Numerous selectable catheter sheaths are shown including a sheath with an integral acoustically-transparent window, sheaths with end extensions that aid in positioning, a liquid injection-producing sheath, a sheath having its window section under tension employing an axially loaded bearing, a sheath carrying a dilatation or positioning balloon over the transducer, a sheath carrying a distal rotating surgical tool and a sheath used in conjunction with a side-viewing trocar.

Acoustic imaging catheter and the like

Growing community of inventors

Concord, MA, United States of America

Lucien A Couvillon, Jr