Fidia Farmaceutici S.p.a.

Nanogetic S.l.

Other

Consiglio Nazionale Delle Ricerche

Università Degli Studi Di Catania

Sciuto, Sebastiano

Luciano Messina

Susanna Vaccaro

Vincenza Corsa

Alessandro Negro

Salvatore Pernagallo

Laura Pilotto

Luca Musumeci

Sebastiano Sciuto

Valentina Greco

Enrico Rizzarelli

Juan Diego Unciti Broceta

Rosario Maria Sanchez Martin

Giovanni Gennari

Salvatore Caruso

Antonella Schiavinato

Francesco Bellia

Valeria Lanza

Rosanna Inturri

Cristina Satriano

Pharmaceutical compositions are described containing Hyaluronic Acid and Carnosine for use in the treatment and prevention of osteoarthritis (OA) and for the treatment of rheumatoid arthritis (RA).

Pharmaceutical compositions containing hyaluronic acid and carnosine and relative use

Disclosed is a nanoparticle system consisting of a polymer support or substrate in the form of nanoparticles to which a hydrolase enzyme able to degrade hyaluronic acid and one or more biologically and/or pharmacologically active molecules are covalently bonded, its preparation process and its uses in the diagnostic, prognostic and therapeutic fields.

Nanosystems for controlled transport of active molecules for diagnostic, prognostic and therapeutic purposes

The present invention relates to a hyaluronidase from, applications thereof and a method for the production thereof.

Bacterial hyaluronidase and process for its production

The present invention relates to a derivative of carnosine (&#x3b2;-alanyl-L-histidine) having formula (1), obtained by the functionalization of hyaluronic acid with carnosine.

Derivatives obtained from hyaluronic acid and carnosine

A process for preparingATCC 31394 hyaluronidase by obtaining hyaluronidase having molecular weight of 21.6 kDalton, which has hyaluronidase activity and stability markedly higher than those of the hyaluronidase obtained from such microorganism to date.

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The present invention relates to a method for the production of hyaluronic acid (HA) inandthrough plasmid vectors wherein the gene is under the control of strong promoter P, and a system for the selection of stable bacterial strains for the production of high levels of hyaluronic acid.

The present invention relates to a method for the production of hyaluronic acid (HA) inandthrough plasmid vectors wherein the gene is under the control of strong promoter Pgrac, and a system for the selection of stable bacterial strains for the production of high levels of hyaluronic acid.

Method for obtaining recombinant host bacterial cells that produce hyaluronic acid

Growing community of inventors

Abano Terme, Italy

Luciano Messina