Isf S.p.a.

I.s.f. Societa Per Azioni

Luciano Dorigotti

Mario Pinza

Giorgio Pifferi

Teodoro Fonio

Valerio Aliverti

Giovanni Gaviraghi

Claudio Semeraro

Francesco Parravicini

Carlo Carpi

Compositions for the treatment of osteoporosis and related diseases comprise calcitonin and, as an absorption enhancer, a glycyrrhizinate.

Pharmaceutical compositions for intranasal administration of calcitonin

Compositions comprising a calcitonin gene related peptide and, as an absorption enhancer, a glycyrrhizinate.

Calcitonin gene related peptide

There are described new alkoxyalkylidenhydrazinopyridazines having antihypertensive activity having the formula: ##STR1## wherein R is alkyl or cycloalkyl having up to 5 carbon atoms, optionally substituted with unsubstituted phenyl, substituted phenyl or cycloalkyl, R.sub.1 is hydrogen or alkyl having 1 to 3 carbon atoms and R.sub.2 is alkyl having 1 to 3 carbon atoms, a carboxylic group or phenyl and the process for their preparation.

Alkoxyalkylidenhydrazinopridazines and process for their preparation

Antihypertensive compounds comprising hydrazinopyridazine derivatives of the formula: ##STR1## wherein R is an alkyl radical containing from 1 to 4 carbon atoms or an alkyl radical having from 1 to 4 carbon atoms substituted with a hydroxy group and R.sub.1 is a hydrogen atom, an alkyl radical containing from 1 to 4 carbon atoms, a phenyl or 3-pyridyl group and their non-toxic pharmaceutically acceptable salts with inorganic or organic acids. Also pharmaceutical compositions containing the same.

Acylated hydrazinopyridazine antihypertensives

6-SUBSTITUTED 3-CARBETHOXYHYDRAZINOPYRIDAZINES OF THE GENERAL FORMULA: ##STR1## wherein R.sub.1 and R.sub.2, which may be the same or different, represent a lower alkyl group containing from 1 to 6 carbon atoms, an allyl group, a 2-hydroxyethyl group or a 2-hydroxypropyl group, as well as the pharmaceutically acceptable salts thereof. Also a method of preparation. These compounds have anti-hypertensive activity.

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Milan, Italy

Luciano Dorigotti