Massachusetts Institute of Technology

Lucene Tong

Michael S Feld

Rebecca Rae Richards-Kortum

Richard P Rava

Carter Kittrell

Ramachandra Rac Dasari

Joseph J Baraga

Kyungwon An

Robert M Cothren

Paola Taroni

Young D Park

Anand V Mehta

A method for laser induced fluorescence of tissue in which laser radiation is used to illuminate and induce fluorescence in the tissue under study to determine the chemical composition or pathologic condition of tissue. The laser radiation and the retrieved fluorescing radiation can be conveyed through a catheter using an array of optical fiber. The fluorescence spectrum of the tissue can be displayed and analyzed to obtain information regarding the chemical composition and medical condition of the tissue inside the human body.

Method for laser induced fluorescence of tissue

The present invention relates to a method and apparatus for diagnosing the condition of gastrointestinal tissue. The method and apparatus excite fluorophores within a portion of gastrointestinal tissue with a laser to cause the fluorophores to emit fluorescent radiation. The presence of abnormal tissue is then determined by detecting the radiation emitted by the excited fluorophores and comparing the emitted radiation to a reference emission for fluorophores within normal tissue at predetermined wavelengths.

Spectral diagnosis of diseased tissue

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Boston, MA, United States of America

Lucene Tong