Koninklijke Philips Corporation N.v.

Lumileds LLC

Philips Lighting Holding B.v.

Koninkliike Philips N.v.

Lucas Johannes Anna Maria Beckers

Franciscus Johannes Gerardus Hakkens

Peter Dirksen

Edward Theodorus Maria Berben

Mareike K Klee

Cornelis Petrus Hendriks

Willem Franke Pasveer

Joyce Van Zanten

David W Smith

Biju Kumar Sreedharan Nair

Dirk Burdinski

Timon Rutger Grob

Sergei Shulepov

Nicolaas Petrus Willard

Petrus Henricus Maria Timmermans

Kevin Grayson Wickline

Peter Josef Schmidt

Cornelis Reinder Ronda

Johannes Wilhelmus Weekamp

Johan Hendrik Klootwijk

David Andrew Fish

Hans-Peter Loebl

Godefridus Antonius Harks

Vincent Adrianus Henneken

Harm Jan Willem Belt

Joerg Meyer

Herbert J Schreinemacher

Rudolf Maria Jozef Voncken

Sander Theodoor Pastoor

Nico Maris Adriaan De Wild

Denny Mathew

Sima Asvadi

Antonius Maria Rijken

Steven Ernest Franklin

Susanne Maaike Valster

Gerardus Henricus Maria Gijsbers

Baby-Seriyati Schreinemacher

Jan Cornelis Kriege

Antonius Wilhelmus Maria De Laat

Job Lipsch

Thomas Johannes Van Gijsel

Judith Petra Huurdeman

Ronaldus Mathias Hubertus Steijvers

Michael Johan Ferdinand Marie Ter Laak

Sean Scott Wheelhouse

Paulus Hubertus Gerardus Offermans

Nicholaas Petrus Willard

Pawel Michalski

Sergei Y Shulepov

Mareike Klee

Dhilan Skukunan Devadasan

A material for binding to a cell culturing protein is disclosed. The material contains a bulk-modified elastomer comprising a plurality of fatty acid moieties covalently bound to the elastomer bulk, wherein the carboxylic acid groups of said moieties are available to provide said binding. Also disclosed are a fluidic device module, a cell culturing scaffold, a fluidic device, the method of synthesizing such a material and a drug testing method. With such a material, a (monolithic) fluidic device module may be manufactured in as few as a single step injection molding process.

Cell culturing materials

An intraluminal ultrasound imaging device includes a flexible elongate member configured to be positioned within a body lumen of a patient. An ultrasound imaging assembly is disposed at the distal portion of the flexible elongate member. The ultrasound imaging assembly includes a plurality of acoustic elements and an acoustically-transparent window disposed over the plurality of acoustic elements. The acoustically-transparent window comprising a plurality of layers formed on top of one another. The plurality of layers includes an innermost layer directly contacting the plurality of acoustic elements, an outermost layer opposite the innermost layer, and an adhesive layer. The outermost layer includes a tubing. A hardness of the innermost layer is less than hardnesses of every other layer of the plurality of layers. A hardness of the outermost layer is greater than the hardnesses of every other layer of the plurality of layers.

Acoustically transparent window for intraluminal ultrasound imaging device

An imaging device () is disclosed comprising an ultrasound transducer array () having a plurality of ultrasound transducer elements defining an ultrasound emitting surface of the ultrasound transducer array; and an acoustic window () on the ultrasound emitting surface, said acoustic window comprising: a first layer () of a hydrocarbon elastomer contacting the ultrasound emitting surface, said first layer further containing an antioxidant; and a second layer () of a further hydrocarbon elastomer on the first layer, said second layer having a greater Shore A hardness than the first layer. Also disclosed are an ultrasound imaging system () comprising such an imaging device, such as catheter (), and a method () of forming an acoustic window () on an ultrasound transducer array () for such a device ().

Imaging device with ultrasound transducer array

A 3D gas chromatography (GC) column development is possible by assembly of two parts each being substrates formed by gas tight materials. One part may be a silicon substrate with a snake shaped flow channel structure and the other part may be a glass plate. Both are coated with a column packing comprising polubutadiene, which is also able to glue or bond both parts together, thereby sealing the flow channel, thus forming a GC column. The column packaging can be composed in all kinds of polarity from very hydrophobic till very hydrophilic. In this way the column packing can be tuned on resolution for particular molecules which are interesting to detect, e.g. Octane. The invention is advantageous for micro GC columns.

Gas chromatography column with polybutadiene coating

An ultrasound device () is disclosed comprising a transducer arrangement () and an acoustically transmissive window () over said arrangement, said window comprising an elastomer layer () having conductive particles dispersed in the elastomer, the elastomer layer having a pressure-sensitive conductivity, the ultrasound device further comprising an electrode arrangement () coupled to said elastomer layer and adapted to measure said pressure-sensitive conductivity. An ultrasound system and arrangement including such an ultrasound device are also disclosed.

Ultrasound device contacting

A pliable cover adapted to cover an active area of an ultrasound probe is described. The ultrasound probe includes a plurality of ultrasound transducer elements. The pliable cover includes a polymer layer that holds a coupling agent () that couples the ultrasound transducer elements to a body surface and a regular pattern of channels extending through the pliable cover. An ultrasound probe arrangement is also described and includes the pliable cover. An ultrasound system including the ultrasound probe arrangement, and a method of positioning the ultrasound probe in a region of a body are also described.

Ultrasonic head comprising a pliable cover with a regular pattern of apertures

An acoustic lens suitable for a CMUT array () is provided. The acoustic lens comprising: a first layer () comprising a thermoset elastomer having a polymeric material selected from hydrocarbons, wherein the first layer has an inner surface () arranged to face the array and an outer convex shaped surface () arranged to oppose the inner surface; and a second layer () coupled to the outer surface of the first layer and comprising thermoplastic polymer polymethylpentene and an elastomer selected from the polyolefin family (POE) blended therein, wherein the outer layer located at the outer surface of the acoustic window layer, wherein the first layer has a first acoustic wave velocity (v) and the second layer has a second acoustic wave velocity (v), said second velocity is larger than the first acoustic wave velocity.

Acoustic lens for an ultrasound array

An ultrasound array for acoustic wave transmission comprising at least one capacitive micro-machined ultrasound transducer (CMUT) cell (), wherein the CMUT cell comprises a substrate (); a first electrode (); a cell membrane () having a second electrode ('), which opposes the first electrode and the substrate with a cavity () there between, wherein the membrane is arranged to vibrate upon the cell activation; and an acoustic window layer (), overlaying the cell membrane, and having an inner surface opposing the cell membrane and an outer surface. The acoustic window layer comprises a first layer comprising molecules of antioxidant and a polymeric material () with insulating particles () embedded therein, wherein the polymeric material consists of hydrogen and carbon atoms and has a density equal or below 0.95 g/cmand an acoustic impedance equal or above 1.45 MRayl. This acoustic window layer provides an improved acoustic performance, such as wide bandwidth and low attenuation, in application with the CMUT based array.

CMUT array comprising an acoustic window layer

A wearable patch () is disclosed comprising an ultrasound transducer () mounted on the patch and a fluid reservoir () for containing a coupling agent () for the ultrasound transducer, said fluid reservoir being delimited by a portion () of the patch and a seal ring () extending from the patch, said seal ring surrounding the ultrasound transducer and comprising a plurality of fluid conduits () extending from the fluid reservoir at least partially through the seal ring. Also disclosed are a wearable patch kit, assembly and application method.

Wearable ultrasound patch and application method of such a patch

A wearable patch () comprising an ultrasound transducer () mounted on the patch, the ultrasound transducer comprising a major surface for contacting the skin of a wearer of the patch, said major surface being covered by a layer () of a soluble adhesive precursor, the wearable patch further comprising a seal ring () extending from the patch, said seal ring surrounding the ultrasound transducer. Also disclosed are a wearable patch kit, assembly and application method.

Skin-contact products with a transpiration function such as medical devices or medicinal products, of which face masks, aspirators, ventilators, breast pumps or wound dressings are examples are described especially a skin-contact product with a transpiration function with an improved microclimate at a patient interface material-skin contact area. In an embodiment a material system is described that comprises a hydrophobic silicone base material and a hydrophilic silicone material that is combined with the hydrophobic base material.

Skin-contact product having moisture and microclimate control

An acoustical lens () for an ultrasound probe () is disclosed. The acoustical lens comprises an inner surface () for facing an emission surface () of an ultrasound transducer () and for receiving ultrasound waves from the ultrasound transducer. The acoustical lens further comprises an outer surface () for emitting the ultrasound waves received at the inner surface, wherein the inner surface is formed as a convexly curved surface and wherein at least one recess () is associated to an edge of the inner surface for capturing mold material.

Acoustical lens and ultrasound transducer probe

An acoustic window layer for an ultrasound array, which layer has an inner surface arranged to face the array and an outer surface arranged to face a patient, and comprising an outer layer comprising a thermoplastic polymer selected from a polyolefin family (TPO) and an elastomer selected from the polyolefin family (POE) blended therein, wherein the outer layer located at the outer surface of the acoustic window layer. In a preferred embodiment the blend comprises a copolymer of ethylene-octene and polymethylpentene. The thermoplastic polyolefin provides the blend with mechanical, chemical stability and low acoustic wave attenuation; whilst the polyolefin elastomer provides a possibility to tune the acoustic impedance of the blend and to further improve its acoustic wave propagation properties.

Acoustic window layer for an ultrasound array

An electrode configured to provide electrical contact with skin of a subject is provided. The electrode includes an electrode body configured to be removably coupled with the skin of the subject and to receive electrical signals from and/or transmit electrical signals to the skin of the subject, and an electrical coupling that facilitates coupling the electrode to an external computing system. The electrode body includes a conductive silicone material configured to enable uptake or diffusion of moisture from the skin of the subject over which the electrode body is disposed; and a detergent configured to facilitate a flow of ions through the conductive silicone material.

Dry electrode for bio-potential and skin impedance sensing and method of use

An illumination system comprising a radiation source and a monolithic ceramic luminescence converter comprising a composite material of at least one luminescent compound, and at least one non-luminescent compound, wherein the material of the non-luminescent compound comprises silicon and nitrogen, is advantageously used, when the luminescent compound comprises an rare-earth metal-activated host compound also comprising silicon and nitrogen. Shared chemical characteristics of the luminescent compound and the non-luminescent material improve phase assemblage, thermal and optical behavior. The invention relates also to a composite monolithic ceramic luminescence converter.

Illumination system comprising composite monolithic ceramic luminescence converter

Growing community of inventors

Veldhoven, Netherlands

Lucas Johannes Anna Maria Beckers