Vdyne, Inc.

Aria Cv, Inc.

Hlt, Inc.

Lucas Harder

Robert M Vidlund

Mark R Christianson

Neelakantan Saikrishnan

Scott A Kramer

David J Holtan

John P Gainor

Craig A Ekvall

Karl Vollmers

John Scandurra

Chad Perrin

Lynn M Zwiers

Cameron Vidlund

Miles Wing

Hendrik De Hoog

Piramiah Elayaperumal

Katherine Soojian

Marc Knutson

David Holtan

An implantable device for reducing pulsatile pressure within a blood vessel is described herein, for example to treat pulmonary hypertension. The implantable device may include a fluid reservoir, a compliant member (e.g., a balloon), and a conduit coupled to the fluid reservoir and the compliant member. Advanced designs for anchoring the compliant member in the blood vessel are described. In addition, enhanced reservoir, conduit, and balloon designs, as well as methods for implanting/using the same, are provided.

Implantable devices for reducing pulsatile pressure within a blood vessel

The invention relates to anchor channels and subannular anchors for a transcatheter heart valve replacement, and in particular for an orthogonally delivered transcatheter prosthetic heart valve having a annular support frame having compressible wire cells that facilitate rolling and folding the valve length-wise, or orthogonally to the central axis of the flow control component, allowing a very large diameter valve to be delivered and deployed to the tricuspid valve from the inferior vena cava or superior vena cava, or trans-atrially to the mitral valve, the valve having a height of about 5-60 mm and a diameter of about 25-80 mm, without requiring an oversized diameter catheter and without requiring delivery and deployment from a catheter at an acute angle of approach.

Cinch device and method for deployment of a side-delivered prosthetic heart valve in a native annulus

The invention relates to anchor channels and subannular anchors for a transcatheter heart valve replacement (A61F2/2412), and in particular for an orthogonally delivered transcatheter prosthetic heart valve having a annular support frame having compressible wire cells that facilitate rolling and folding the valve length-wise, or orthogonally to the central axis of the flow control component, allowing a very large diameter valve to be delivered and deployed to the tricuspid valve from the inferior vena cava or superior vena cava, or trans-atrially to the mitral valve, the valve having a height of about 5-60 mm and a diameter of about 25-80 mm, without requiring an oversized diameter catheter and without requiring delivery and deployment from a catheter at an acute angle of approach.

A delivery system for side-delivery of a prosthetic valve includes a compression device defining a lumen having a first perimeter at a proximal end that is larger than a second perimeter of the lumen at a distal end. A loading device is coupleable to the compression device and defines a lumen having substantially the second perimeter. A distal end of the loading device includes a first gate that is movable between an open state and a closed state to at least partially occlude the lumen of the loading device. A delivery device defines a lumen having substantially the second perimeter. A proximal end of the delivery device is coupleable to the distal end of the loading device and includes a second gate movable between an open state and a closed state to at least partially occlude the lumen of the delivery device.

Delivery and retrieval devices and methods for side-deliverable transcatheter prosthetic valves

A side-deliverable prosthetic heart valve includes an outer frame and a flow control component. The outer frame has a supra-annular region, a subannular region, and a transannular region therebetween. The flow control component is mounted to the outer frame such that at least a portion of the flow control component is disposed in the transannular region. The prosthetic valve has a delivery configuration for side-delivery via a delivery catheter and is expandable when the prosthetic valve is released from the delivery catheter. The subannular region of the outer frame is disposable in a first configuration as the prosthetic valve is seated in an annulus of a native heart valve and is transitionable to a second configuration after the prosthetic valve is seated in the annulus of the native heart valve.

Side-deliverable transcatheter prosthetic valves and methods for delivering and anchoring the same

A device for reducing pulsatile pressure within a vessel to treat heart disease, such as pulmonary hypertension, includes a compliant body structured to expand and contract upon changes in pressure within the vessel, a reservoir structured for holding a fluid therein, and a conduit extending between and fluidly coupling the reservoir and the compliant body, wherein the device includes a graphene-polymer composite designed to resist diffusion of the fluid through the device.

Diffusion resistant implantable devices for reducing pulsatile pressure

A braided support structure that folds upon release from a delivery device wherein said fold is at least partially effected by varying the pic angle of the braids at locations where the folding is desired.

Braided support structure

Growing community of inventors

Minneapolis, MN, United States of America

Lucas Harder