Technische Universiteit Delft

Campina B.v.

Lucas Antonius Maria Van Der Wielen

Geert-Jan Witkamp

Geert Jan Witkamp

Marcel Ottens

Gerard Willem Hofland

Marijana Golubovic

Clemens Johannes Willibrordus K&ouml;llmann

The invention relates to a method of preparing a protein aggregate, wherein an aqueous protein solution is acidified with a pH that lies above the isoelectric point of the protein. In accordance with the invention, a first protein, which through acidification is able to form a protein aggregate, is acidified in the presence of a second protein in the aqueous solution in order to form a coaggregate comprising the first and second protein, wherein the second protein under identical temperature conditions and pH does not form a protein aggregate in the absence of the first protein. Acidification preferably occurs with the aid of CO.

Method of preparing a protein aggregate and a pharmaceutical preparation

A method for isolating casein and calcium phosphate as separate products from a milk source, comprising the steps of: a) contacting the milk source with carbon dioxide under pressure in order to precipitate the casein; b) separating the casein from the milk source while maintaining the pressure to obtain a casein fraction and a whey fraction; and c) releasing the pressure from the whey fraction to allow calcium phosphate to precipitate therefrom.

Method for the sequential precipitation of casein and calcium phosphate from a milk source

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Bleiswijk, Netherlands

Lucas Antonius Maria Van Der Wielen