Istituto Europeo Di Oncologia S.r.l.

Ifom - Istituto Fondazione Di Oncologia Molecolare Ets

Luca Sartori

Mario Varasi

Paola Vianello

Raffaella Amici

Ciro Mercurio

Anna Cappa

Alessia Romussi

Loris Moretti

Manuela Villa

Giuseppe Meroni

Simona Polo

Paolo Trifiro′

Paolo Trifiro'

Elisa Zagarri

The present application relates to compounds of formula (I), wherein A, R, R, and Rare as defined in the specification, pharmaceutical compositions containing such compounds and to their use in therapy. 

Indole derivatives as histone demethylase inhibitors

The present invention relates to imidazole derivatives, wherein A, R, R, and Rare as defined in the specification, pharmaceutical compositions containing such compounds and to their use in therapy. 

Imidazoles as histone demethylase inhibitors

The present invention relates to imidazole derivatives of Formula (I), wherein A, R, R, and Rare as defined in the specification, pharmaceutical compositions containing such compounds and to their use in therapy. 

The present application relates to thienopyrrole derivatives, compounds of Formulas (I) and (Ia), wherein R, R, Rand Rare as defined in the specification, pharmaceutical compositions containing such compounds and to their use in therapy. The compounds of the application can be useful for inhibiting KDM1 and the prevention and/or treatment of cancer, infectious disease, or a disease characterized by aberration of cellular energy metabolism, e.g., obesity. 

Thienopyrroles as histone demethylase inhibitors

Growing community of inventors

Brunate, Italy

Luca Sartori