Centre National De La Recherche Scientifique

Universitè De Montpellier

Université Montpellier 2 Sciences Et Techniques

Université Montpellier I

Luca Cipelletti

Hervé Cottet

Jean-Philippe Biron

Michel Martin

A method for determining the size distribution of a mixture of molecule or particle species including the steps of: injecting a sample of the mixture to be analyzed inside a capillary in which an eluent is flowing; transporting the sample injected along the capillary from an injection section to a detection section thereof, in experimental conditions suitable to generate a Taylor dispersion phenomenon that is measurable at the level of the detection section; generating, by a suitable sensor included in the detection section, a signal characteristic of the Taylor dispersion of the transported sample; processing the detection signal in order to obtain an experimental Taylor signal S(t); and analyzing the experimental Taylor signal &#x15c;(t), wherein the step of analyzing an experimental Taylor signal &#x15c;(t) of a sample of the mixture consists of searching an amplitude distribution P(G) that allows the experimental Taylor signal &#x15c;(t)' to be broken down into a sum of Gaussian functions.

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Montpellier, France

Luca Cipelletti