Merck Patent Gmbh

Emd Millipore Corporation

Centre National De La Recherche Scientifique

Millipore Corporation

Universitéde Strasbourg

Luc Felden

Stephane Olivier

Pierre Woehl

Gael Waiche

Sebastien Ribault

Didier Metz

Sébastien Ribault

Pierre Guedon

Frederick G Bargoot

Emmanuelle Simon

Sebastien Jouette

David Lehmann

Stéphane Olivier

Frederic Marc

David Squires

Jean-Jacques Richert

Marisa Hohnadel

Frédéric Marc

Florian Allard

Christophe Collet

Ola Ahmad

Marine Bouthillon

Sebastian Jouette

Gaël Waiche

An apparatus () for removing moisture from a surface () in a container ('), characterized by: a centrifuging element comprising a mount () for attaching said container (&#x2032;) to said centrifuging element and a drive () coupled to said mount () for rotating said attached container (&#x2032;) and centrifuging said moisture off said surface () in said attached container (&#x2032;); and a heating element () for providing heat energy and evaporating said moisture from said surface () in said attached container (&#x2032;), and a corresponding method.

Apparatus and method for removing moisture from a surface in a container

A fluid transfer device comprising a first reservoir () having a predetermined sub-ambient pressure and volume and a presealed opening (), a second reservoir () containing a predetermined volume of a fluid (M) and having a presealed opening (), and a chamber () having an internal space () and an inlet () to the space () adapted to be connected to the opening () of the second reservoir () and an outlet () from the space () adapted to be connected to the opening () of the first reservoir ().

Fluid transfer device and process of aseptically transferring a fluid

The present invention is directed to a method for detection of microbial colonies on a surface, comprising the steps of obtaining one or a plurality of digital images I0, I1, I2, I3, I4 of the surface, said digital images I0, I1, I2, I3, I4 being represented by at least two-dimensional matrices of pixel values, calculating a statistical noise distribution based on at least one of the digital images I0, applying the statistical noise distribution calculated in the calculation step to the one or the plurality of digital images I0, I1, I2, I3, I4, and detecting an object of interest as a candidate for a microbial colony based on deviation of pixel values from the noise distribution.

Method for early detection and identification of microbial-colonies, apparatus for performing the method and computer program

An apparatus for performing sonication on liquid samples comprises a rack for holding an array of sample vials, an ultrasonic probe with an arrangement of recesses corresponding to the array of sample vials and adapted to respectively receive and contact an outer surface of a bottom portion of a respective one of the sample vials, and a counter-holder with an arrangement of pushing members corresponding to the array of sample vials and adapted to respectively apply a force to a respective one of the sample vials so as to push the bottom portion of each vial into contact with the associated recess of the probe. The apparatus can be used in a method of preparing a sample for detection of cell components (e.g. cell analyte, proteins, nucleid acids etc.) and applying sonication within certain parameter ranges which can provide a universal lysis method that can be applied to a large variety of cells or organisms like all bacteria, viruses, spores, yeast and mold within the same apparatus and process.

Apparatus for performing sonication

The invention provides a filtering and centrifugation device, comprising a barrel, a volume in the barrel for receiving a fluid sample to be processed, a filter medium, at least one piston movable in the barrel to force fluid in the volume through the filter medium to produce a filtrate, and a space for pelleting particulate material. The device is centrifugeable, and said space is located in or communicates with the volume and is located preferably away from the filter medium such that the particulate material does not or at least not completely clog the filter medium during such centrifugation of the device. The invention also provides a method for the sterile filtration of a sample, comprising the steps of introducing the sample into the volume of such a device, subjecting the device to centrifugation to pellet particulate material contained in the sample at the space away from the filter medium, and applying force to the piston(s) to force fluid of the sample in the volume through the filter medium to produce a filtrate. By providing the space for pelleting the particulate material under the influence of the centrifugation force, the clogging of the filter medium can be avoided or considerably delayed. Further, the entire process can be performed in the same device without having to remove the sample for any intermediate clarification steps.

Method and device for centrifugation and filtration

A device () for separating a membrane () to analyze from a support (), the membrane being mounted in a frame (), itself mounted on a support, having a body () comprising a longitudinal recess () for translational reception of the assembly constituted by the frame mounted on the support, the recess having a first end () and a second end () and longitudinal sides (A,B,) facing each other between said two ends, the device having bearing means () for a first member of the frame/support group between the first and the second end of the recess, which are adapted to serve as a bearing for the first member of the frame/support group once the assembly is disposed in the recess, each of the sides having a ramp (A,B,) adapted to engage a gripping member () of the second member of the frame/support group when the assembly is translationally moved from the first to the second end, said ramps being adapted to separate the support from the frame during said translational movement by bearing on said gripping member of the second member of the frame/support group, the first member of the frame/support group then bearing on the bearing means, such that the frame and the support are separated once the translational movement has arrived at the second end.

Device for separating a membrane from a support

A method comprising obtaining a preparation unit comprising a filter module and a collection for each liquid coming from the filter module, with the filter module comprising an inlet compartment as well as an evacuation compartment for the liquids, the filter and collection modules being rotatably mounted relative to each other; disposing the filter and collection modules in a first position; passing a liquid from the filter module to attain the collection module; disposing the filter and collection modules relative to each other in a second position, and passing another liquid from the filter module to attain the collection module.

Unit and method for preparing a sample for the microbiological analysis of a liquid

The unit comprises a filter membrane filter module and a collection module for liquid coming from the filter module, with the filter module comprising an inlet compartment as well as an evacuation compartment for the liquids, the filter and collection modules being rotatably mounted relative to each other. The method comprises the step of obtaining such a unit, of disposing the filter and collection modules in a first position, of passing a liquid from the filter module to attain the collection module, of disposing the filter and collection modules relative to each other in a second position, and the step of passing another liquid from the filter module to attain the collection module.

Unit for preparing a sample for the microbiological analysis of a liquid

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Andolsheim, France

Luc Felden