General Electric Company

Other

Ge Precision Healthcare LLC

Generla Electric Company

Lowell Scott Smith

David Martin Mills

Douglas Glenn Wildes

Charles Edward Baumgartner

Peter William Lorraine

Robert Stephen Lewandowski

Axel F Brisken

Robert Gideon Wodnicki

Rayette Ann Fisher

Kai Erik Thomenius

Venkat Subramaniam Venkataramani

Warren Lee

Wei-Cheng Tian

Christopher Robert Hazard

Charles Gerard Woychik

Kwok Pong Chan

Thomas Kwok-Fah Foo

Vadim Bromberg

Kenneth Wayne Rigby

Joseph Edward Piel, Jr

Slawomir Rubinsztajn

William A Edelstein

Bruno Hans Haider

John R Logan

Reinhold Bruestle

Jeffrey Bernard Fortin

Frederic Lanteri

Rowland W Redington

Jean-Francois Gelly

Jhimli Mitra

Chester Frank Saj

Charles W Eichelberger

Anil Raj Duggal

William E Engeler

William P Kornrumpf

Marshall Gordon Jones

Matthew N O'Donnell

John Eric Tkaczyk

Kevin Matthew Durocher

Lionel M Levinson

Paul Arthur Bottomley

Glenn Scott Claydon

Otward M Mueller

Sandeep Narendra Gupta

Lewis Jones Thomas, Iii

Luca Marinelli

Stacey Joy Kennerly

Tunc Icoz

Steinar Bjaerum

Soumya Ghose

Desmond Teck Beng Yeo

William Macomber Leue

George Charles Sogoian

Theodore Lauer Rhyne

Deva N Pattanayak

Matthew Harvey Krohn

Bryan P Bednarz

Steven G Karr

Dimitrios Vatis

Dominic Michael Graziani

Bo Wang

David R Eisner

Serge Gerard Calisti

Michael S Horner

Raymond J Hodsoll, Jr

Xuan-Ming Lu

Roberta Marie Strigel

Svein Bergstoel

Ye-Ming Li

Stanley Chu

Hyon-Jin Kwon

Edward J Piel, Jr

Jerry T Harrison

Robert J Wojnarowksi

Wiliam P Kornrumpf

James Hartman Holmes

Timothy James Fiorillo

Chi Tat Chiu

Kedar Anil Patwardhan

Christopher Stephen Yetter

Stephen Royal Kaiser

Stephen Edwardsen

Jie Sun

Sam Yie-Sum Wong

Nim Hak Tea

Yung Sheng Liu

A grid of phased array transducers includes a piezoelectric layer and a plurality of ground contact traces. The piezoelectric layer includes a first side and a second side. The plurality of ground contact traces is disposed on the first side of the piezoelectric layer along an elevational direction, where each ground contact trace of the plurality of ground contact traces extends along an azimuthal direction. Further, each phased array transducer of the grid of phased array transducers is disposed between an adjacently disposed pair of ground contact traces of the plurality of ground contact traces. Moreover, each phased array transducer includes at least a portion of at least one ground contact trace of a corresponding pair of ground contact traces, and where each phased array transducer includes a plurality of transducer elements.

Phased array transducers and wafer scale manufacturing for making the same

The subject matter discussed herein relates to the automatic, real-time registration of pre-operative magnetic resonance imaging (MRI) data to intra-operative ultrasound (US) data (e.g., reconstructed images or unreconstructed data), such as to facilitate surgical guidance or other interventional procedures. In one such example, brain structures (or other suitable anatomic features or structures) are automatically segmented in pre-operative and intra-operative ultrasound data. Thereafter, anatomic structure (e.g., brain structure) guided registration is applied between pre-operative and intra-operative ultrasound data to account for non-linear deformation of the imaged anatomic structure. MR images that are pre-registered to pre-operative ultrasound images are then given the same nonlinear spatial transformation to align the MR images with intra-operative ultrasound images to provide surgical guidance.

Deformable registration for multimodal images

A system and method for providing virtual real-time MRI-guidance for a biopsy outside of a conventional MRI scanner is described. MR images and ultrasound images of a region of a patient's body are simultaneously acquired during a pre-biopsy procedure. Respiratory states that the patient may experience during the biopsy are then determined from the acquired ultrasound images, and each respiratory state is associated with corresponding MR images. The MR images are indexed with their corresponding respiratory state. Ultrasound images are then acquired of the patient during a biopsy procedure. The respiratory state of the patient is determined from the ultrasound images, and the corresponding indexed MR images are displayed.

Image-guided biopsy techniques

An ultrasound transducer includes a transducer array having a plurality of transducer elements. The transducer array has a first side and a second side. Further, one or more ground electrodes are disposed on the first side of the transducer array, and one or more signal electrodes are disposed on the second side of the transducer array. Moreover, an acoustic backing structure is operatively coupled to the plurality of transducer elements of the transducer array. Also, a plurality of electrical traces is routed on a surface of the acoustic backing structure and operatively coupled to at least one of the one or more signal electrodes and one or more ground electrodes.

Ultrasound transducers having electrical traces on acoustic backing structures and methods of making the same

Methods and systems using magnetic resonance and ultrasound for tracking anatomical targets for radiation therapy guidance are provided. One system includes a patient transport configured to move a patient between and into a magnetic resonance (MR) system and a radiation therapy (RT) system. An ultrasound transducer is also provided that is hands-free and electronically steerable, securely attached to the patient, such that the ultrasound transducer is configured to acquire four-dimensional (4D) ultrasound images concurrently with one of an MR acquisition or an RT radiation therapy session. The system also includes a controller having a processor configured to use the 4D ultrasound images and MR images from the MR system to control at least one of a photon beam spatial distribution or intensity modulation generated by the RT system. The system determines the previously-acquired correct MR images that represent a specific motion state at some time, t, by a plurality of transformations that allow the representation of the position of fiducial markers in the corresponding ultrasound images to match that of a prior ultrasound acquisition.

Methods and systems to determine respiratory phase and motion state during guided radiation therapy

A manufacturing a process is provided for the bulk manufacture of transducer arrays, including arrays having at least one 3D printed (or otherwise additive manufactured) acoustic matching layers. In certain implementations, the manufactured transducers include a composite-piezoelectric transducer on a de-matching layer. In one implementation, by producing multiple arrays at once on a common carrier, and by using direct-deposit additive processes for the matching layers, the described processes greatly reduce the number of parts and the number of manual operations.

Method for manufacturing ultrasound transducers

A method for forming a tileable detector array is presented. The method includes forming a detector module, where forming the detector module includes providing a sensor array having a first side and a second side, where the sensor array includes a first plurality of contact pads disposed on the second side of the sensor array, disposing the sensor array on an interconnect layer, where the interconnect layer includes a redistribution layer having a first side and a second side, where the redistribution layer includes a second plurality of contact pads disposed on the first side, an integrated circuit having a plurality of through vias disposed therethrough, where a first side of the integrated circuit is operationally coupled to the second side of the redistribution layer, where the sensor array is disposed on the interconnect layer such that the first plurality of contact pads on the second side of the sensor array are aligned with the second plurality of contact pads on the first side of the redistribution layer, operationally coupling the first plurality of contact pads on the second side of the sensor array to the second plurality of contact pads on the redistribution layer to form a sensor stack, coupling the sensor stack to a substrate to form the detector module, and tiling a plurality of detector modules on a second substrate to form the tileable detector array.

Tileable sensor array

An ultrasound system is provided for imaging an object. The ultrasound system includes an ultrasound probe for acquiring ultrasound data and a cooling subsystem for actively removing heat from the ultrasound probe. The cooling subsystem includes a pump disposed within a reservoir containing a coolant and configured to circulate the coolant through the ultrasound probe via a conduit.

System and method for actively cooling an ultrasound probe

The present invention provides novel filled silicone compositions comprising a nano-particulate metal oxide filler selected from nano-particulate monoclinic alpha-phase bismuth oxide, nano-particulate erbium oxide, and mixtures thereof. The new composite compositions exhibit a combination of outstanding performance characteristics in both the cured and uncured states. Thus, the uncured formulations are typically free flowing liquids which are self-leveling, which de-gas readily under vacuum, are readily colorable through the addition of pigments, and which cure at temperatures of about 60&#xb0; C. The cured compositions possess outstanding acoustic characteristics which make them ideally suited for use in applications such as acoustic lenses for medical imaging and therapy. For example, the acoustic impedance of compositions provided by the present invention is closely matched to the acoustic impedance of human tissue. This may result in an enhancement of ultrasound transmission efficiency between the lens of an ultrasound probe comprising such a composition and the patient.

Silicone rubber compositions comprising bismuth oxide and articles made therefrom

A system for improving the acoustic performance of an ultrasound transducer by reducing artifacts within the acoustic spectrum is disclosed. The system includes an acoustic layer having an array of acoustic elements, a dematching layer coupled to the acoustic layer and having an acoustic impedance greater than an acoustic impedance of the acoustic layer, and an interposer layer coupled to the dematching layer and comprising a substrate and a plurality of conductive element. The interposer layer is formed to have an acoustic impedance lower than the acoustic impedance of the dematching layer. The ultrasound transducer also includes an integrated circuit coupled to the interposer layer and electrically connected to the array of acoustic elements through the dematching layer and the interposer layer.

Ultrasound transducer with improved acoustic performance

A method for Fresnel zone imaging is provided. The method comprises identifying a plurality of constructive regions and a plurality of destructive regions in an energy transmitting device and converting the destructive regions to the constructive regions by using an apodization profile. The apodization profile comprises apodization values for each constructive region and destructive region and the apodization values comprise real numbers.

Fresnel zone imaging system and method

An acoustical stack for an ultrasound probe comprises a piezoelectric layer having top and bottom sides and a plurality of matching layer sections forming a matching layer structure. Each of the matching layer sections comprises a spring layer comprising a first material and a mass layer comprising a second material that is different than the first material. The spring layer within the matching layer section that is positioned closest to the piezoelectric layer is thinner than the spring layer within the other matching layer sections.

Method for forming a matching layer structure of an acoustic stack

A method for making a testable sensor assembly is provided. The method includes forming a first sensor array on a first substrate having a first side and a second side, wherein the first sensor array is formed on the first side of the first substrate, coupling a first semiconductor wafer having a first side and a second side to the first sensor array, wherein the first side of the first semiconductor wafer is coupled to the first sensor array, thinning one of the second side of the first substrate or the second side of the first semiconductor wafer, and testing the first sensor array to identify operational and non-operational units in the testable sensor assembly before integration of the sensor assembly with interface electronics.

Methods of making and using integrated and testable sensor array

A capacitive micromachined ultrasound transducer (cMUT) cell is presented. The cMUT cell includes a lower electrode. Furthermore, the cMUT cell includes a diaphragm disposed adjacent to the lower electrode such that a gap having a first gap width is formed between the diaphragm and the lower electrode, wherein the diaphragm comprises one of a first epitaxial layer or a first polysilicon layer. In addition, a stress reducing material is disposed in the first epitaxial layer.

Capacitive micromachined ultrasound transducer fabricated with epitaxial silicon membrane

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Niskayuna, NY, United States of America

Lowell Scott Smith