Milliken Research Corporation

Milliken + Co

Other

Delphi Oracle Corp.

Louis Dischler

Jimmy B Henson

Roger Milliken

Scott W Efird

Dale Robert Williams

Wesley M Drexler

Roy Phillip Demott

Wolfgang K Otto

Terry T Moyer

Disclosed are methods for the removal of plaques containing amyloid beta, protecting the brain from amyloid beta toxicity, and restoring neurological function by the expansion of neural stem cell pools and improving mitochondrial health.

Methods and compositions for the treatment of neurological diseases and syndromes of aging

Disclosed are methods and compositions for reducing the epigenetic age of organisms, especially that of adult humans, which provide for proliferating endogenous stem cells, removing aberrant epigenetic marks from chromosomes and mitochondrial DNA, and replacement of senescent cells.

Methods for restoring stem cell pools and reducing epigenetic age

Compositions for promoting the endogenous self-renewal of stem cells

Methods for reducing mitochondrial dysfunction

Disclosed are methods and compositions of reducing the epigenetic age of mammalian organism, especially an adult human of geriatric age. The methods provide for the proliferation of endogenous stem cells using mitochondrial fusion and a UCP2 blocker or other stimulants; supplying stem cells with nutrition to prevent cell cycle arrest; and removal of senescent somatic cells using senolytic treatments. The proliferation of endogenous neural stem cells after plaque removal for the treatment of Alzheimer's is also disclosed.

Methods and compositions for rapidly decreasing epigenetic age and restoration of more youthful function

Compositions for reducing mitochondrial dysfunction

The inventive method provides highly desirable hand to various different types of fabrics through the initial immobilization of individual fibers within target fabrics and subsequent treatment through abrasion, sanding, or napping of at least a portion of the target fabric. Such a procedure includes 'nicking' the immobilized fibers thereby permitting the fibers to produce a substantially balanced strength of the target fabric in the fill and warp directions while also providing the same degree of hand improvements as obtained with previous methods. Furthermore, this process also provides the unexpected improvement of non-pilling to synthetic fibers as the 'nicking' of the immobilized fibers results in the lack of unraveling of fibers and thus the near impossibility of such fibers balling together to form unwanted pills on the fabric surface. Fabrics treated by this process are also contemplated within this invention.

Abraded fabrics exhibiting excellent hand properties and simultaneously high fill strength retention

Desirable hand fabrics exhibiting low fill tensile strength loss after physical treatments

Range-dyed fabrics that possess excellent hand characteristics and simultaneously exhibit substantially nondirectional appearances are provided. Such a combination permits the production and utilization of an extremely comfortable apparel fabric that can be attached to any other similar type of fabric to form a target apparel article without the time-consuming need to align such component fabrics to ensure an overall aesthetic appearance is met for the target apparel article. In general, such a fabric is produced through the initial immobilization of individual fibers within target fabrics and subsequent treatment through abrasion, sanding, or sueding of at least a portion of the target fabric. Such a procedure produces a fabric of short pile height and desirable hand. Upon range-dyeing the target fabric exhibits the extra benefit of nondirectional surface characteristics. The ability to produce such specific fabrics without the need for jet-dyeing thus provides a significant cost advantage to the manufacturer and consumer.

Method of producing non-directional range-dyed face finished fabrics

A pile of a pile fabric is subjected to a forward abrasive action and a reverse abrasive action. The pile of the pile fabric obtains disturbances and/or fibrils on the ends of the piles.

Pile fabric having conditioned pile ends

A bi-modal closure for a container opening is provided. The closure has a first mode intended for adult use, wherein the closure is readily opened, and a second child-resistant mode, wherein the closure is more difficult to open, especially by children. The conversion between modes is accomplished by use of a bi-stable element located in the closure.

Convertible child-resistant closure with invertible bi-stable spring element

Range-dyed face finished fabrics exhibiting non-directional surface fiber characteristics

A zipper is provided wherein at least one stringer has a row of coupling elements presenting a variable visual appearance along the coupled length of the zipper. The zipper has improved aural, tactile or visual aesthetics, and is more difficult to counterfeit.

Zipper stringer having coupling elements with variable properties

A process for angularly sueding a textile web containing fill and warp yarns with the steps of: supplying the web, controlling the tension of the web, engaging the web with at least one diamond-coated abrasive treatment roll disposed at an abrasion angle, rotating the treatment roll at a surface speed different from that of the web, and taking up the supplied web. A preferred embodiment comprises a pair of spaced treatment rolls disposed at an abrasion angle, and rotating in opposite directions relative to the web. The related apparatus for this specific process is also provided.

Abraded high fill strength fabrics substantially free from discoloration streaks

A compact push-pull exercise apparatus having a partial turn outer cam surface in contact with a random surface such as a floor, and one or more handles rotatably mounted to the cam rotational axis. The operator begins an exercise cycle in the kneeling position with hands on the handles and with arms generally near the vertical position. The operator pushes the apparatus forward to a stopping position with the operator nearly prone. During the first portion of the forward movement, gravitational energy is stored as the cam rotational axis is lifted. As the operator reverses the movement from the prone position to the kneeling position, gravitational energy is released during the first portion of the in-stroke to ease the return motion during the most difficult portion of the exercise cycle.

Growing community of inventors

Spartanburg, SC, United States of America

Louis Dischler