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Arch Development Corporation

Louis Cohen

Anthony Thomas Reder

Richard A Rose

Barry G Arnason

Ewa E Chelmicka-Schorr

The present invention discloses improved methods for the treatment of autoimmune diseases using .beta.-adrenergic agonists, and particularly, .beta..sub.2 -adrenergic agonists. The treatment of animals with either EAE or EAN using the .beta..sub.2 -adrenergic agonist terbutaline significantly suppressed clinical disease. A Phase I safety treatment trial with terbutaline was conducted in MS patients. Twenty-four patients were treated for 4 weeks. No obvious side effects were observed. At 4 weeks, 15 of the 24 patients improved on neurologic rating scale and 17 patients reported subjective improvement. Treatment of rats with EAMG, an animal model of t

Use of .beta.-adrenergic agonists to treat patients with demyelinating

A capacitance-type fluid level sensing system, method, and device is disclosed for determining the amount of fluid in a container, for example, a disposable plastic bag used for intravenous (i.v.) injection or collection of waste from a human body (catheter). In one illustrated embodiment, conductive plates are disposed on the outside of the plastic bag and connected to a circuit for detecting any change in the capacitance of the capacitor formed thereby. In another embodiment, the conductive plates are integrally constructed as part of a surface of the electronic device housing, such that the fluid level can be detected when the housing is affixed directly to the outside of the bag. Alternative annunciation, detection, flow rate calculation, display, and housing features are shown in various embodiments.

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Chicago, IL, United States of America

Louis Cohen