Wake Forest University

Other

American Southeast Medical Technologies, LLC

Louis Charles Argenta

Michael J Morykwas

Nicole Hope Levi

William D Wagner

Jie Jerry Liu

David Loren Carroll

Lawrence Xavier Webb

Stephen Tatter

Jie Liu

Nicole H Levi

James Eric Jordan

Christopher Michael MacNeill

Rui Wang

Tabitha Rosenbalm

Nichole H Levi

Elizabeth Grace Gurysh

James E Jordan

Christopher Michael Macneill

Elizabeth Grace Graham

The present invention provides devices and methods that treat damaged spinal cord tissue, such as spinal tissue damaged by disease, infection, or trauma, which may lead to the presence of swelling, compression, and compromised blood flow secondary to interstitial edema.

Devices and methods for treating spinal cord tissue

The present invention relates to nanoparticle compositions and, in particular, to composite polymeric nanoparticle compositions. A composite nanoparticle described herein comprises a photoluminescent polymeric component and a photo-thermal polymeric component. The photoluminescent polymeric component and the photo-thermal polymeric component can each comprise a single polymeric species or multiple polymeric species.

Composite polydots and applications thereof

Nanofiber-based biomaterials containing fibroin for wound repair and tissue replacement and, more particularly, heart valve replacement.

Nanofiber-based graft for heart valve replacement and methods of using the same

A method and apparatus are provided for treating cardiac tissue to modulate ischemic heart tissue with topical sub-atmospheric pressure to minimize cell death and damage.

Apparatus and method for cardiac tissue modulation by topical application of vacuum to minimize cell death and damage

A tissue treatment apparatus and method are provided for treating tissue by the application of the time-varying sub-atmospheric pressure. The apparatus includes a cover adapted to cover a wound and adapted to maintain sub-atmospheric pressure the site of the wound. The apparatus further includes a source of suction configured to generate a time-varying sub-atmospheric pressure having a periodic waveform comprising a gradual change in pressure. The suction source cooperates with the cover to supply the time-varying sub-atmospheric pressure under the cover to the wound. The time-varying sub-atmospheric pressure may vary between a first pressure value below the inherent tissue tension of the wound tissue and a second pressure value above the inherent tissue tension of the wound tissue.

Apparatus and method for wound treatment employing periodic sub-atmospheric pressure

A biphasic material and devices comprising the same are provided for the development of conductive conduits that may be used for the treatment of peripheral nerve injury. These devices or conduits are designed such that repeated electric field gradients can be initiated to promote neurite and axonal outgrowth. Conducting conduits using doped synthetic and/or natural polymers create specifically patterned high and low conducting segmented materials, which are mechanically used to produce the electrical properties needed for nerve conduits. These electrical properties stimulate neurite outgrowth and axonal repair following a peripheral nerve transection.

Conduit for peripheral nerve replacement

An external fixation assembly includes a plurality of hollow pins that are inserted into a patient's bone. Each pin has an interior bore and a plurality of apertures extending through the pin wall from the bore. The pin may be coupled to a source of vacuum pressure operable to create reduced pressure in the tissue surrounding the pin. A cover is placed around the pin and sealed to provide a fluid-tight enclosure that maintains reduced pressure around the pin. A method for applying external fixation using the fixator pins described above includes the steps of inserting each pin through a skin opening, positioning the pin apertures near selected tissue, covering the skin opening with a sealed enclosure, connecting the pins to a source of vacuum pressure, and activating the source of vacuum pressure to create reduced pressure in the patient's tissue at or near the bone.

External fixation assembly and method of use

The present invention relates generally to a device and method for treating tissues of the central nervous system and more particularly, but not exclusively, to a device and method for treating the brain tissue.

Device and method for treating central nervous system pathology

The present invention describes a corrective headgear for treating infants having abnormal head shape or torticollis. In an embodiment, the headgear comprises a protective shell having a curvilinear surface, wherein the curvilinear surface is positioned to overlie at least a portion of the cranium of an infant, to thereby prevent the infant from resting its head on the regions of the skull underneath the surface of the shell. In an embodiment, the headgear comprises a cloth cap that wraps around the shell to position the shell on the infant's head. Also in an embodiment, the shell comprise a convex protrusion positioned on the shell to prevent the infant from resting its head on regions of the skull protected by the headgear.

Growing community of inventors

Winston-Salem, NC, United States of America

Louis Charles Argenta