3m Innovative Properties Company

Minnesota Mining and Manufacturing Company

Louis C Haddad

Jerald K Rasmussen

James I Hembre

Steven M Heilmann

Gary J Drtina

Frederick W Hyde

Donald F Hagen

Catherine A Bothof

George W Griesgraber

Kannan Seshadri

Robert T Fitzsimons, Jr

Yi He

Erin A Satterwhite

Robert E Perkins

Matthew T Scholz

Moses Mekala David

Dean M Moren

Todd W Johnson

Philip D Eitzman

Robert A Pranis

Caroline M Ylitalo

Mahfuza B Ali

Robin Edgar Wright

Nicholas A Lee

Diane R Wolk

Brian J Gates

Craig G Markell

Yifan Zhang

Narina Y Stepanova

Richard L Walter

Michael J Svarovsky

Linda K M Olson

Jessica M Buchholz

Daniel Sarpong

Wanda Bahmet

David B Olson

Kurt J Halverson

Robert A Asmus

Tushar A Kshirsagar

Dong-Wei Zhu

G Marco Bommarito

Joel R Dufresne

Brian Kenneth Nelson

Douglas A Hanggi

William E Foltz

Michael G Williams

Sanjay L Patil

Francois Ahimou

Joseph J Stoffel

Barbara C Swenson

Keith M Hoffmann

Madhusudan Raghavachari

Garold L Goken

Kent A Orlandini

Mitchell D Erickson

David C Seely

Susan K Dallas

Theresa J Wilson

Jerald K Rassmussen

Robert T Fitzsimons

Ligand functionalized substrates, methods of making ligand functionalized substrates, and methods of using functionalized substrates are disclosed.

Ligand functionalized polymers

A composition is disclosed. The composition comprises at least one polymeric colorant having a polymer component with a colorant component covalently bound thereto, a medicament, and a liquid vehicle. The at least one colorant component does not react directly or indirectly with the medicament. Methods of using the polymeric colorants, including a method for the preparation of skin as a site for a surgical procedure and a method of treating a medical condition, are also provided.

Polymeric colorant compositions and methods of use

Sterilization indicators that include a neutralizer, such indicators useful for testing the effectiveness of a sterilization procedure by measuring the activity of an active enzyme whose activity is correlated with the survival of microorganisms.

Self-contained sterilization indicators including a neutralizer for residual oxidizing sterilant

Polymeric beads and methods of making the polymeric beads are described. The polymeric beads are crosslinked hydrogels or dried hydrogels. The polymeric beads are formed from droplets of a precursor composition that are exposed to radiation. The droplets are totally surrounded by a gas phase. The precursor composition contains a polar solvent and a polymerizable material miscible in the polar solvent. The polymerizable material has an average number of ethylenically unsaturated groups per monomer molecule equal to at least 1.2.

Polymeric beads and methods of making polymeric beads

A method of separating a target biological species from a fluid is disclosed comprising contacting the fluid with a ligand-functionalized polymer comprising:

A method for testing efficacy of a protease enzyme assay, the method comprising providing an enzyme which acts as a surrogate enzyme control for the protease enzyme; combining the surrogate enzyme control with an assay substrate for the protease enzyme; and determining a change in the assay substrate resulting from the surrogate enzyme control acting on the assay substrate; wherein the protease enzyme is selected from the group consisting of metalloproteinases, serine proteases, and cysteine proteases; a method for conducting a protease enzyme assay using the method for testing efficacy; a kit including an enzyme which acts as a surrogate enzyme control for a protease enzyme in testing efficacy of a protease enzyme assay; and a method of releasing the kit are provided.

Methods and kit for protease enzyme assays

Polymeric fibers and methods of making the polymeric fibers are described. The polymeric fibers are crosslinked hydrogels or dried hydrogels that are prepared from a precursor composition that contains polymerizable material having an average number of ethylenically unsaturated groups per monomer molecule greater than 1.0. The polymeric fibers can contain an optional active agent.

Polymeric fibers and methods of making

The present invention provides materials, methods, and kits for reducing nonspecific binding of molecules to a surface, particularly in a solid phase material, and more specifically a solid phase material that includes a hydrophobic portion, by contacting the solid phase material with a fluorinated nonionic surfactant comprising two or more fluorinated hydrophobic segments and one or more hydrophilic segments.

Materials, methods, and kits for reducing nonspecific binding of molecules to a surface

Surface coatings including azlactone-functional hydrogels and articles with the coatings disposed thereon are disclosed. Methods of making the coating and controlling the gellation time of the hydrogels are also disclosed.

Azlactone-functional hydrophilic coatings and hydrogels

Materials for use in miniaturized arrays, the arrays, and methods of manufacturing. Materials for making arrays described include a substrate with a silicon-containing layer, optionally with linking agents and reactants.

Array comprising diamond-like glass film

The present invention provides a method for isolating nucleic acid from a sample, preferably from a biological sample. This method involves applying the biological sample to a hydrophobic organic polymeric solid phase to selectively trap target nucleic acid and removing nucleic acid with a nonionic surfactant. Another method involves treating a hydrophobic organic polymeric material with a nonionic surfactant, washing the surface, and subsequently contacting the treated solid organic polymeric material with a biological sample to reduce the amount of nucleic acid that binds to the organic polymeric solid phase.

Method for reducing the amount of nucleic acid adhering to a hydrophobic surface

Fluid handling devices including a substrate with a diamond-like film. The devices include capillaries and microfluidic articles.

Fluid handling devices with diamond-like films

Growing community of inventors

Mendota Heights, MN, United States of America

Louis C Haddad