Minntech Corporation

Renal Systems, Inc.

Other

Medtronic, Inc.

Daniel T. Pigott

David T. Kesler

Louis C. Cosentino

Jeffrey A. Lee

Louis C Cosentino

Paul D Brinda

Robert T Hall, Ii

Felix J Martinez

Larry E Fuller

Jeffrey A Lee

Daniel A Baker

Ulf-Eiel F Bach

LeRoy J Fischbach

Jo-Ann B Maltais

Raymond F Cracauer

Perry L Blackshear, Jr

William H Harm

Bill H Niemi

Robert G Andrus

Stuart L Gallant

John P Silbernagel

Randal M Wenthold

Jamshed R Cooper

B Steven Springrose

Rosario M Marino

Anatol M Hnojewyj

Wayne I Nelson

Bruce P Amiot

Walter B Jansen

Daniel T Pigott

Elias Klein

Peter Stasz

James Leo Campbell

Richard A Helms

Richard P Goldhaber

Roger L Funk

Edward J Mikolajczyk

Daniel Theodore West

Richard A Ward

Michael R Birnbaum

Ronald L Wathen

David C Gust

Paul H Hess

John E Briddon

David T Kesler

Robert F Reggin

Harold Lee Massie

Louis Seiler

Igor P Zdorov

Gerald J Rinehart

Scott R Vagle

Earnest R Caine

F Jesus Martinez

Russel L Hoeker

Vernon S Taaffe

William P Burkinshaw

Kimberly L Hall

A method for improving priming of an integrated oxygenator and heat exchanger which includes pretreating the integrated hollow fiber oxygenator and heat exchanger device with a surfactant. Pretreating the device coats the interior surfaces of the integrated hollow fiber oxygenator and heat exchanger with the surfactant, which facilitates the removal of entrapped air. An integrated hollow fiber oxygenator and heat exchanger having a surfactant coating on the interior surfaces is provided which subsequently allows for more efficient priming with an aqueous priming media.

Oxygenator priming method

A method is provided for priming a hollow fiber oxygenator which is integrated with a hollow tube heat exchanger. A closed priming circuit is created between a cardiosurgery reservoir, the combined hollow fiber oxygenator and heat exchanger and a vacuum source. Vacuum pressure is applied to the closed priming circuit to evacuate the residual air from the circuit. Priming solution is released from the cardiosurgery reservoir and fills the evacuated closed priming circuit.

Method for priming a hollow fiber oxygenator

An asymmetrical, microporous, hollow fiber membrane is made from a polymeric dope mixture of polysulfone and polyvinyl pyrrolidone dissolved in an aprotic solvent. The physical morphology of the hollow fiber membrane, i.e., the asymmetric microporous wall, is rapidly formed by passing the polymeric dope mixture through an outer annular orifice of a tube-in-orifice spinneret while simultaneously passing a precipitating solution through the central tube of the spinneret. The emerging hollow fiber travels substantially downward for about 0.01-10 m before submersion into a quenching bath. The asymmetrical, microporous, hollow fiber membrane is biocompatible and suitable for use in, for example, dialysis, hemodialysis, ultrafiltration, and water filtration applications.

Hollow fiber membranes and method of manufacture

A low prime, high heat exchange efficiency oxygenator is provided which includes an oxygenation portion and a heat exchanger portion. Disposed within the heat exchanger portion is a hollow tube heat exchanger wound bundle which includes a plurality of hollow tubes knitted into a mat, the mat wound under tension into a bundle which includes from 16 to 24 layers of the mat. The oxygenator provided permits prime volumes of 180 to 240 mLs.

Wound heat exchanger oxygenator

An asymmetric, microporous hollow fiber membrane comprising a polyimide is disclosed. The hollow fiber membrane is chemically inert to aqueous solutions and/or blood, is immediately rewettable after repeated steam and chemical sterilizations, has superior clearance, sieving, and water permeability characteristics and is usable over a wide range of applications such as dialysis and water filtration. Also disclosed is the process for manufacturing the polyimide hollow fiber membrane.

A stable, shippable microbicidal composition including between about 0.2 to 8% hydrogen peroxide, about 0.2 to 11% peracetic plus acetic acid, 0 to about 1.0% sequestrant such as organic phosphonic acid or its salt and water, and surfactant between 0 and about 1% with the ratio of total acid to H.sub.2 O.sub.2 being between about 1.0 and 11.

Stable, shippable, peroxy-containing microbicide

A combination heat exchanger and oxygenator device is provided. The device includes a generally cylindrical housing having first and second compartments with hollow heat exchange tubes and hollow gas exchange tubes disposed therein, a blood inlet, a blood outlet, a heat exchanges medium inlet, a heat exchange medium outlet, an oxygenating fluid inlet and an oxygenating fluid outlet. The housing has a central axis with the second compartment being concentric thereto. The blood flow passage is defined by blood entering the device generally axially through a path extending along the central axis of the housing and flows generally radially through the second, oxygenating compartment.

Cylindrical blood heater/oxygenator

A unique hollow fiber filter cartridge that allows repeated autoclaving without any deleterious breaks in sealing integrity between the potted fiber bundle and the filter module is disclosed. The unique filter cartridge braodly includes a casing that has at least one open end with an inner lip in the casing proximal to the open end; and a porous collar that has first and second peripheral edges, at least one of which is coupled to the casing along the inner ledge.

Hollow fiber filter having a porous collar/ring seal

A method of sealingly coupling a hollow fiber bundle having first and seconds ends to a porous collar having first and second peripheral edges, at least one of which is coupled to the inner ledge of a casing for encasing said bundle of hollow fibers is disclosed. The method broadly includes providing a porous collar having first and second outer peripheral edges; providing a casing having first and second longitudinal ends, the casing defining a central chamber, the chamber having first and second open ends wherein the longitudinal ends of the casing each include an inner lip proximal to the open end; coupling the first outer peripheral edge of the porous collar to the inner lip of the casing; retaining a bundle of hollow fibers having first and second longitudinal ends within the chamber; permeating the longitudinal ends of the hollow fiber bundle with a fluid impermeable material; joining the porous collar to the fluid impermeable material by penetration of the material into the porous collar; and curing the fluid impermeable material. The method provides a fluid impermeable seal between the casing and the individual hollow fibers. The seal prevents the unfiltered fluid from coming into contact with filtrate and provides a strong bond that is impervious to dry heat and steam sterilization at temperatures ranging from 100.degree. C. to 150.degree. C. and pressures from 10 psi to 60 psi.

Method of manufacture of hollow fiber filter cartridge with porous ring

Method of manufacturing of hollow fiber cartridge with porous ring

Stable, anticorrosive peracetic/peroxide sterilant

Sensor for peracetic acid-hydrogen peroxide solution

A stable, shippable microbicide solution, having improved anticorrosive properties comprising a two part system, the first part consists of a mixture of acetic acid, hydrogen peroxide, peracetic acid, and water. This is referred to for brevity as a peroxide/peracid solution. The second consists of water having dissolved therein a wetting agent which is preferably Victawet.RTM. 35B which is the sodium hydroxide reaction product of an aliphatic alcohol and phosphorous pentoxide. Three other Victawet.RTM. agents have proven operative. Alternatively, Fluorad.TM. FC95, which is a agent of potassium perfluoroalkyl sulfonates may be used. The microbicide may also be a premixed one component system containing the anticorrosive agents of the invention.

Anticorrosive microbicide

Growing community of inventors

Plymouth, MN, United States of America

Louis C Cosentino