Other

Nzl Corporation

Louis A Luzzi

Thomas E Needham

Polireddy Dondeti

Joyce K Luzzi

Zia Hossein

The present invention describes a surprising new and effective pharmaceutical composition comprising microparticles and a pharmaceutically acceptable carrier. In particular, the present invention describes a pharmaceutical composition containing microparticles off a matrix material into which is infused a therapeutic agent. The present invention further provides a method of infusing a therapeutic agent such as a protein or peptide into a matrix material to form microparticles containing said therapeutic agent by employing a compressed solvent which is normally gaseous at ambient temperature and pressure. A method is also disclosed of treating or preventing a disease in a mammal by administering to said mammal through a mucosal membrane an effective amount of a pharmaceutical composition comprising microparticles containing a therapeutic agent which effectively treats the disease or disorder.

Method of incorporating proteins or peptides into a matrix and administration thereof through mucosa

A method of treating skin disorders comprises the step of applying thereto a composition wherein the main active ingredient comprises dimethyl isosorbide. It has been found that dimethyl isosorbide has a dermal penetrating action which can effectively carry it to the source of a skin disorder and that it has antifungal, antiviral and antibacterial effects which make it effective in the treatment of a wide range of skin disorders.

Growing community of inventors

Narragansett, RI, United States of America

Louis A Luzzi