Cytiva Sweden Ab

Ge Healthcare Bio-sciences Ab

Lotta Hedkvist

Johan Arthursson

Key Hyckenberg

Petra Bangtsson

Eva Cecilia Olsson

Lena Nyholm

Markus Galin

Thomas Pless

Henrik Larsson

Jill Simon

Elsa Lundblad

Henrik Sundqvist

Markus Ge Healthcare Gallin

Jill Ge Healthcare Simon

Thomas Ge Healthcare Pless

A method of automated configuration in a bioprocess system and to verify a process defined by a flow path representation. The method comprises the steps of: capturing one image of the bioprocess system comprising tubing for the fluid communication between units of the bioprocess system; analyzing the captured image to identify the tubing connecting units of the bioprocess system; producing a processed representation from the captured image wherein at least a part of the tubing is identified; and comparing the processed representation with the flow path representation to verify their functional concordance.

Bioprocess system and method providing automated configuration detection

The present invention relates to a method of automated configuration in a bioprocess system () and to verify a process defined by a flow path representation. The method comprises the steps of: &#x2014;capturing one image of the bioprocess system () comprising tubing () for the fluid communication between units of the bioprocess system (); &#x2014;analyzing the captured image to identify the tubing () connecting units of the bioprocess system (); &#x2014;producing a processed representation from the captured image wherein at least a part of the tubing () is identified; and &#x2014;comparing the processed representation with the flow path representation to verify their functional concordance.

The present invention relates to a method for performing liquid chromatography purification of one or more target molecules from a sample comprising: providing an eluent flow having one or more target molecules, measuring an output parameter indicative of the content of the one or more target molecules in the eluent flow, storing output parameter data, and dividing the eluent flow into consecutive eluent fractions, dividing the output parameter data into corresponding data fractions, in each data fraction obtaining a value indicative of characteristic behavior of the measured output parameter, identifying trends in the measured output parameter based upon the obtained value in consecutive data fractions, and identifying peak(s) in the measured output parameter correlated to eluent fractions based upon the identified trends, whereby information of identified peak(s) and correlated eluent fraction(s) can be presented and purified sample(s) from the eluent may be collected.

Method and apparatus for performing liquid chromatography purification

The present invention relates to automated chromatography systems and software for controlling such automated systems for optimising the purification of a protein from a sample. The software is adapted to monitor the signal from a detector in the system, determine two signal parameters and to control the components of the system depending on the actual values of the two signal parameters.

Purification system

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Uppsala, Sweden

Lotta Hedkvist