Thermo Fisher Scientific (Bremen) Gmbh

Lothar Rottman

Mikhail Belov

A method of operating a collision cell () in a mass spectrometer is disclosed. The collision cell comprises an entrance aperture (), an exit aperture () and electrodes () for producing electric fields. The method comprises feeding ions in a forward axial direction (LD) through the entrance aperture into the collision cell, producing a first electric field to trap ions, and subsequently producing a second electric field to accelerate trapped ions in the forward axial direction. The method further comprises producing a gas flow (G) which is, at least at the entrance aperture () of the collision cell, contrary to the forward axial direction (LD), so as to reduce the kinetic energy of ions in dependence on their collisional cross sections. A collision cell arranged for carrying out the method is also disclosed, as well as a mass spectrometer comprising such a collision cell.

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Bremen, Germany

Lothar Rottman