Biomerieux, Inc.

Commissariat a L'energie Atomique Et Aux Energies Alternatives

Lorène Allano

Frédéric Pinston

Dominique Decaux

Denis Desseree

Corine Fulchiron

Guillaume Boissier

Lorette Lapierre

Léontine Jacolin

Christophe Tachier

Khrystyna Kyrgyzova

Guillaume Sutra

Marthe Lagarrigue-Charbonnier

Marine Depecker

Method for determining microorganism growth in a biological sample likely to contain microorganisms, said biological sample being contained in an analysis container, said analysis container being subjected to an incubation of a determined duration, said method comprising:

Method and system for determining microorganism growth

A method for obtaining a model of an object surface from a plurality of images of said object, wherein the object is illuminated with one or more illumination sources, the method comprising: &#x2022;&#x2014;obtaining a set of images each comprising an array of pixels and representing similar views of an object, wherein the similar views are obtained under different illumination conditions; &#x2022;&#x2014;defining a model function that expresses the known pixel intensity values of the images in terms of the following unknown model components: &#x2022;&#x2014;a first model component (A) representing the albedo of the object at each pixel location and being the same for the plurality of images and being an albedo value; &#x2022;&#x2014;a second model component (L) representing an intensity of illumination for each image and being an illumination source intensity value being the same for all pixels of each image; &#x2022;&#x2014;a third model component (V) representing a specific illumination direction and being different for each image and being an illumination vector and being the same for all pixels of each image; &#x2022;&#x2014;a fourth model component (N) representing surface normal directions of the object surface at each pixel position and being the same for all images and being a normal vector; &#x2022;&#x2014;performing one or more sequences of minimization operations to minimize a difference function between the pixel values obtained from the set of images and pixel values calculated using said model function, each minimization operation being performed by allowing one of said model components (A, L, V, N) to vary while the others remain unchanged; &#x2022;&#x2014;outputting the fourth model component (N) as said model of the object surface.

Method, system and computer program product for producing a raised relief map from images of an object

A method for correcting one or more images of an object () from a plurality of images of the object (), for providing one or more corrected images of the object () for further use in a process for generating a representation of the surface of the object, each image of the plurality of images comprising one or more pixels and each pixel comprising a pixel value, wherein one or more illumination sources () illuminate the object with different directions of illumination, and each image is associated with a determined direction of illumination, the method comprising the steps of: for each pixel of the plurality of a first image of said plurality of images: a) selecting a pixel in the first image for obtaining the pixel value of the selected pixel; b) selecting at least one corresponding pixel in at least one image of the remaining images of the plurality of images for obtaining the pixel value of the at least one selected corresponding pixel; c) calculating at least one ratio of the pixel value of the selected pixel in the first image to each pixel value of the at least one selected corresponding pixel; d) determining a requirement for pixel value correction of the selected pixel on the basis of the at least one calculated ratio; e) calculating a value (W) based on the at least one calculated ratio to determine a corrected pixel value of the selected pixel; f) replacing the pixel value of the selected pixel with the corrected pixel value in the first image to provide a corrected first image.

Method, system and computer program product for improving the quality of an image

An imaging system for generating images of biological samples having a surface, the system comprising: a sample support for supporting a biological sample in use; a plurality of illumination sources, the plurality of illumination sources being arranged around the sample support and each adapted to illuminate the biological sample, in use, from a different direction; an image capture device for capturing illumination which has impinged on the biological sample to thereby form an image of the sample; wherein at least one of the illumination sources direction is not perpendicular to the surface of the sample.

Imaging method and system for analyzing in-vitro biological samples

A method for enhancing an image of a biological sample, which biological sample has been grown in a vessel on a culture medium.

Bio-imaging method and system

Growing community of inventors

Sèvres, France

Lorène Allano