H. Lundbeck A/s

Lone Munch Ringgaard

Michael Harold Rock

Morten Jorgensen

Andre Faldt

Nicholas Moore

Michael J Mealy

André Faldt

Jorgen Brodersen

René Holm

Arne MØRK

Tine Bryan STENSBØL

Morten JØRGENSEN

Jørgen Brodersen

This disclosure relates to a process for the preparation of 1-[2-(2,4-dimethylphenylsulfanyl) -phenyl]piperazine or a pharmaceutically acceptable salt thereof. The process includes reacting compound II with compound III and compound IV in the presence of a solvent, a base and a palladium catalyst. R, R', X, and Xin the formulas above are defined in the Specification.

Process for preparing 1-[2-(2,4-dimethylphenylsulfanyl)-phenyl]piperazine or pharmaceutically acceptable salt thereof

This disclosure relates to a process for the preparation of 1-[2-(2,4-dimethylphenylsulfanyl)-phenyl]piperazine or a salt thereof. The process includes reacting compound II with compound III and compound IV in the presence of a solvent, a base and a palladium catalyst. R, R', X, and Xin the formulas above are defined in the Specification.

Process for preparing 1-[2-(2,4-dimethylphenysulfanyl)-pheny]piperazine or pharmaceutically acceptable salt thereof

Growing community of inventors

Copenhagen, Denmark

Lone Munch Ringgaard