Cogent Biosciences, Inc.

Logan E Vine

Mark Joseph Chicarelli

John Peter Fischer

Martha E Rodriguez

Jennifer Fulton

Leah J Salituro

Ravi Kumar Jalluri

Bradley J Newhouse

Aaron Christopher Smith

John E Robinson

Jay Bradford Fell

Macedonio J Mejia

Cori A Malinky

Vijay Kumar

John I Trujillo

Yeyun Zhou

Brooklynn Venteicher

Paul R Carlson

Payal Chatterjee

Patrick J Sutter

Scott W Niman

Tanna Bettendorf

Robert A Rieger

Lee M Stunkard

Michael L Conner

Hailey J Knox

A compound having the following structure of Formula (IV): or a stereoisomer, salt, or tautomer thereof, wherein R, R, R, A, B, X, and Y are as defined herein. Pharmaceutical composition comprising the compounds, and their use in methods of treating diseases are also described.

Compounds for FGFR inhibition

A compound having the following structure of Formula (I): or a stereoisomer of the compound, tautomer of the compound, pharmaceutically acceptable salt thereof, wherein R, R, R, R, R, R, A, X, Z, and Y are as defined herein.Pharmaceutical composition comprising the compounds, and their use in methods of treating diseases are also described.

PI3K inhibitors

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Boulder, CO, United States of America

Logan E Vine