Lever Brothers Company, Division of Conopco, Inc.

Catexel Limited

Lodewijk Van Der Wolf

Jean Hypolites Koek

Ronald Hage

Wei Zhao

Judith L Kerschner

Ronald P Potman

Jianrong Zhang

Stephen William Russell

Xiaohong Wang

The present invention provides improved processes for the synthesis of 1,4-ditosyl-1,4,7-triazacyclonone, comprising deprotecting a compound of formula (C): wherein P is tosylate or arylsulfonate, with an acidic medium to form 1,2-bis(1,4,7-triazacyclonon-1-yl)-ethane; and subsequently adding formaldehyde and formic acid to the acidic medium to form 1,2-bis-(4,7-dimethyl-1,4,7-triazacyclonon-1-yl)-ethane (Me-DTNE). The syntheses of intermediates are also disclosed.

1,2-bis-(4,7-dimethyl-1,4,7-triazacyclonon-1-yl)-ethane and intermediate for the synthesis of same

A process for preparing a dinuclear manganese complex of formula (A) ##STR1## wherein: Mn represents manganese in the III or IV oxidation state, each X is independently a co-ordinating or bridging species selected from H.sub.2 O, O.sub.2.sup.-, O.sup.2-, OH.sup.-, SH.sup.-, S.sup.2-,&gt;S=O, Cl.sup.-, N.sub.3.sup.-, SCN.sup.-, N.sup.3-, RCOO.sup.-, NH.sub.2.sup.- and NR.sub.3 where R is hydrogen, alkyl or aryl (optionally substituted);

Process for preparing manganese complexes

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Vlaardingen, Netherlands

Lodewijk Van Der Wolf