Other

Ipco, LLC

Restech Research Limited Partnership

Oms Holdings LLC

Lloyd I Osipow

Dorothea C Marra

Joseph G Spitzer

J George Spitzer

Marvin Small

Kevin Claffey

Amiram Carmon

Daniel Lowe

George Spitzer

Aerosol compositions are provided that enhance the therapeutic action of ointments by producing, upon topical application thereof, a sustained cooling effect that provides fast relief form pain and itching as well as a tendency to shrink swollen, inflamed tissue. The compositions contain oils, thickening agents for the oils, and propellant. Aqueous solutions, therapeutic ingredients and various adjuvants may also be present. The specific propellant and the proportion used are selected to provide a deposit with a temperature of about &minus;5&deg; C. to about &plus;5&deg; C. In this temperature range, the deposit is cold enough for the required therapeutic effect, but not so cold as to cause pain or tissue damage. The choice and proportion of thickening agents used are selected to provide a deposit that does not flow or spread. Were the deposit to spread, it would present a large surface area from which propellant present in the deposit would evaporate rapidly. By avoiding spreading, the propellant evaporates more slowly and the cooling effect is more sustained.

Aerosol ointment compositions for topical use

Antiperspirant and deodorant or deodorant compositions with enhanced water absorbency are obtained by including in the compositions gelatin along with means for raising its sol-gel transition temperature.

Deodorant and/or antiperspirant compositions

A shaving preparation is provided that boils above about 50.degree. C. and that rapidly generates a stable shaving lather when rubbed on the skin. The composition is an aqueous soap (a neutralized fatty acid) solution containing a foam generating ingredient, a non-volatile, water-insoluble organic liquid and free fatty acids. Thus, the fatty acids mixture of this invention consists of both free fatty acids and neutralized fatty acids (soap). An unexpected rise in the boiling point occurs when the total fatty acids present are in an amount greater than 11% by weight and where 50 to 85% by weight of the total fatty acids are neutralized fatty acids.

Self-lather generating shaving compositions

Compositions and a process for manufacture are provided for synthetic polymer-propellant systems that form cohesive foamed structures from which aqueous solutions can be expressed, where the useful temperature range over which these structures form is broadened by using a propellant mixture consisting predominantly of a propellant that is a poor solvent for the polymer and has a vapor pressure in the range of 10-35 psig at 20 C in combination with a small amount of a propellant that is a good solvent for the polymer; and where these coherent foamed structures can be formed even with aqueous solutions containing 0 to about 30% alcohol, provided that insoluble fine-particle solids that do not pack and become difficult to redisperse are included in the composition.

Process for the manufacture of synthetic polymer propellant systems

Compositions and a process for manufacture are provided for synthetic polymer-propellant systems that form cohesive foamed structures from which aqueous solutions can be expressed, where the useful temperature range over which these structures form is broadened by using a propellant mixture consisting predominantly of a propellant that is a poor solvent for the polymer and has a vapor pressure in the range of 10-35 psig at 20.degree. C. in combustion with a small amount of a propellant that is a good solvent for the polymer; and where these coherent foamed structures can be formed even with aqueous solutions containing 0 to about 30% alcohol, provided that insoluble fine-particle solids that do not pack and become difficult to redisperse are included in the composition.

Synthetic polymer propellant systems

An underarm deodorant suspensoid stick that is essentially free from any tendency to cause iritation is obtained by suspending in a gelled water-insoluble organic liquid powdered sodium bicarbonate having a particle size in the range of esentially 100% less than 44 micron and at least about 25% greater than 1 micron.

Deodorant stick

A shaving preparation is provided which has a sub-atmospheric vapor pressure at ambient temperature and which generates a lather when applied to the skin. The composition comprises a water-insoluble volatile organic liquid having a vapor pressure substantially below atmospheric pressure, an aqueous soap solution and a surface active agent which together promote the volatilization of the organic liquid, thereby generating a lather as well as reducing the tendency of the volatile organic liquid to cause smarting of the skin. The compositions of this invention are capable of being packaged in a collapsible tube without premature expansion in the tube during storage, shipment and use.

Self-lather generating shaving composition

Shampoo compositions are provided in unpressurized containers that generate a small, tight-bubbled lather more rapidly and more profusely than conventional shampoos, thereby improving the ease with which the shampoo is spread through the hair and rinsed away, resulting in more uniform cleansing. The compositions contain an aqueous solution of a water-soluble salt of lauryl sulfate, a volatile hydrocarbon or halogenated hydrocarbon boiling in the range of 25 C to 50 C, a tertiary amine oxide, and a sufficient amount of water-soluble gum to give the shampoo a viscosity in the range of about 1000 to 20,000 centistokes at 5 C.

Instant lathering shampoo

Synthetic polymer-propellant compositions are provided that are capable of forming foamed structures having a temperature at least 30.degree. C. below ambient temperature and containing open and/or closed cells, which may optionally contain a material which is deposited in the pores and/or walls of the structure as the structure is formed, and comprising:

Synthetic polymer-propellant compositions forming cold foamed structures

A disposable electrode comprising an annulus of foam, a substantially uniform electrode gel in a central region of the annulus, a conductive layer in the electrode gel and making electrical contact with it, and a cap over the conductive layer, electrode gel and annulus of foam. The electrode is made in a plastic tray by placing said annulus in a recess in the tray, placing the conductive layer on the annulus, pouring hot electrode gel into the center region of the annulus, covering the gel with the cap and covering the tray with a sheet whcih is heat sealed to the tray with the electrode inside.

Stable gel electrode

A process is provided for preparing propellant compositions including a film-forming synthetic polymer that are capable of forming foamed structures containing open and/or closed cells, which may optionally contain a material which is deposited in the pores and/or walls of the structure as the structure is formed, which comprises coating the synthetic polymer in particulate form with an inert solid material insoluble in the propellant and in solutions of the synthetic resin the propellant at atmospheric temperature; and then adding the propellant and dissolving the synthetic polymer in the propellant. The process is of particular application for preparing such synthetic polymer-propellant compositions in situ in closed containers capable of withstanding an internal pressure sufficient to keep the propellant in the liquid phase at atmospheric temperature, and when the composition is withdrawn from the container to atmospheric pressure, the propellant volatilizes rapidly and a foamed structure is formed within a few seconds.

Process for preparing propellant compositions forming foamed structures

An improved gel comprises a first polymer that dissolves, disperses or hydrates in hot water and forms or can be made to form a rigid gel on cooling, a second polymer that is insoluble in hot water and that dissolves or hydrates on cooling and is compatible with said hot water soluble polymer, and water. The gel is made by combining the first polymer and water, heating the resulting solution enough that the first polymer dissolves or hydrates, adding the hot water insoluble polymer, and then cooling.

Highly stable gel, its use and manufacture

A process for conditioning hair is provided which comprises applying to the hair an alcohol-soluble fraction of soybean lecithin in solution in a lower alkanol having two or three carbon atoms, thereby lubricating the hair and facilitating combing, and at the same time reducing the accumulation of an electrostatic charge on the hair during combing, and thereby inhibiting fly-away.

Process for conditioning hair

The invention provides a process and apparatus for delivering from a delivery port of an aerosol container having a vapor tap valve a spray of low flammability of a liquid aerosol composition containing a flammable liquefied propellant, which comprises mixing together liquid aerosol composition and gaseous propellant; subjecting the gas/liquid mixture to the constraint imposed by a flow constriction; expanding the gas/liquid mixture; subjecting the gas/liquid mixture to the constraint imposed by a second flow constriction, and again expanding the gas/liquid mixture and then passing the mixture through the remainder of the vapor tap valve to the delivery port; with each constraint and expansion increasing the gas:liquid volume ratio of the mixture and reducing the flammability of the mixture as a delivered spray.

Aerosol container with flameless delivery valve

Aerosol antiperspirant compositions are provided that are highly concentrated with respect to the active astringent salt, and capable of being dispensed from aerosol containers of the foam type at a low delivery rate, comprising, in combination, an astringent salt in an amount within the range from about 8 to about 30%; a liquefied propellant, or a mixture of liquefied propellants, each with a vapor pressure at 21.degree. C. of at least 2.4 atmospheres absolute, having a low molecular weight, in an amount of at least 0.15 mole per atmosphere absolute pressure in the container at 21.degree. C. per 100 g of composition; a nonvolatile miscible organic liquid in an amount within the range from about 0.1 to 30% by weight of the composition; a bulking agent in an amount within the range from about 0.1 to about 5% by weight of the composition; and a solid aliphatic carboxylic acid having from about fourteen to about twenty-two carbon atoms in a straight chain and in an amount within the range from about 0.1 to about 5% by weight of the composition to enhance adherence of the antiperspirant salt to the skin.

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New York, NY, United States of America

Lloyd I Osipow